Preliminary study on the safety and efficacy of a new polymyxin B‐immoblized resin column in treatment of LPS‐induced sepsis beagles

Preliminary study on the safety and efficacy of a new polymyxin B‐immoblized resin column in treatment of LPS‐induced sepsis beagles

Abstract Background This study aims to assess the safety and efficacy of direct hemoperfusion using a new polymyxin B‐immobilized resin column (disposable endotoxin adsorber, KCEA) in an endotoxin/ lipopolysaccharide (LPS)‐induced sepsis model. Methods Eighteen beagles were randomized into 1 interve...

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Bibliographic Details
Main Authors: Yonggui Li, Zhenggen Yang, Jialiang Hu, Zhennan Lin
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Animal Models and Experimental Medicine
Subjects:
endotoxin
hemoadsorption
polymyxin B sulfate
resin
sepsis
Online Access:https://doi.org/10.1002/ame2.12199

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