Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing
After conventional molecular and serologic testing failed to diagnose the cause of illness, deep sequencing identified spotted fever group Rickettsia DNA in a patient’s blood sample. Sequences belonged to R. honei, the causative agent of Flinders Island spotted fever. Next-generation sequencing is p...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2017-11-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/23/11/17-0474_article |
| _version_ | 1819119304413544448 |
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| author | Rikki M.A. Graham Steven Donohue Jamie McMahon Amy V. Jennison |
| author_facet | Rikki M.A. Graham Steven Donohue Jamie McMahon Amy V. Jennison |
| author_sort | Rikki M.A. Graham |
| collection | DOAJ |
| description | After conventional molecular and serologic testing failed to diagnose the cause of illness, deep sequencing identified spotted fever group Rickettsia DNA in a patient’s blood sample. Sequences belonged to R. honei, the causative agent of Flinders Island spotted fever. Next-generation sequencing is proving to be a useful tool for clinical diagnostics. |
| first_indexed | 2024-12-22T06:02:39Z |
| format | Article |
| id | doaj.art-17a8f990bda54bf889de58189ca832f8 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-22T06:02:39Z |
| publishDate | 2017-11-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-17a8f990bda54bf889de58189ca832f82022-12-21T18:36:30ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592017-11-0123111911191310.3201/eid2311.170474Detection of Spotted Fever Group Rickettsia DNA by Deep SequencingRikki M.A. GrahamSteven DonohueJamie McMahonAmy V. JennisonAfter conventional molecular and serologic testing failed to diagnose the cause of illness, deep sequencing identified spotted fever group Rickettsia DNA in a patient’s blood sample. Sequences belonged to R. honei, the causative agent of Flinders Island spotted fever. Next-generation sequencing is proving to be a useful tool for clinical diagnostics.https://wwwnc.cdc.gov/eid/article/23/11/17-0474_articleRickettsiaspotted fever groupgenomebacteriaDNAsequence analysis |
| spellingShingle | Rikki M.A. Graham Steven Donohue Jamie McMahon Amy V. Jennison Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing Emerging Infectious Diseases Rickettsia spotted fever group genome bacteria DNA sequence analysis |
| title | Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing |
| title_full | Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing |
| title_fullStr | Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing |
| title_full_unstemmed | Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing |
| title_short | Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing |
| title_sort | detection of spotted fever group rickettsia dna by deep sequencing |
| topic | Rickettsia spotted fever group genome bacteria DNA sequence analysis |
| url | https://wwwnc.cdc.gov/eid/article/23/11/17-0474_article |
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