tascCODA: Bayesian Tree-Aggregated Analysis of Compositional Amplicon and Single-Cell Data

tascCODA: Bayesian Tree-Aggregated Analysis of Compositional Amplicon and Single-Cell Data

Accurate generative statistical modeling of count data is of critical relevance for the analysis of biological datasets from high-throughput sequencing technologies. Important instances include the modeling of microbiome compositions from amplicon sequencing surveys and the analysis of cell type com...

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Bibliographic Details
Main Authors:	Johannes Ostner, Salomé Carcy, Christian L. Müller
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-12-01
Series:	Frontiers in Genetics
Subjects:	bayesian modeling dirichlet multinomial microbiome data single-cell data spike-and-slab lasso tree aggregation
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2021.766405/full

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