Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis

Extracellular vesicles (EVs) have been regarded as one of the most potential diagnostic biomarkers for different cancers, due to their unique physiological and pathological functions. However, it is still challenging to precisely analyze the contents and sources of EVs, due to their heterogeneity. H...

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Bibliographic Details
Main Authors: Lei Qiu, Xingzhu Liu, Libo Zhu, Liqiang Luo, Na Sun, Renjun Pei
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/13/1/129
Description
Summary:Extracellular vesicles (EVs) have been regarded as one of the most potential diagnostic biomarkers for different cancers, due to their unique physiological and pathological functions. However, it is still challenging to precisely analyze the contents and sources of EVs, due to their heterogeneity. Herein, we summarize the advances in technologies for a single EV analysis, which may provide new strategies to study the heterogeneity of EVs, as well as their cargo, more specifically. Furthermore, the applications of a single EV analysis on cancer early diagnosis are also discussed.
ISSN:2079-6374