Tertiary lymphoid structures associate with improved survival in early oral tongue cancer

Tertiary lymphoid structures associate with improved survival in early oral tongue cancer

Abstract Background The clinical significance of tertiary lymphoid structures (TLSs) is not well-documented in early oral tongue squamous cell carcinoma (OTSCC). Methods A total of 310 cases of early (cT1-2N0) OTSCC were included in this multicenter study. Assessment of TLSs was conducted on hematox...

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Bibliographic Details
Main Authors: Alhadi Almangush, Ibrahim O. Bello, Amr Elseragy, Jaana Hagström, Caj Haglund, Luiz Paulo Kowalski, Pentti Nieminen, Ricardo D. Coletta, Antti A. Mäkitie, Tuula Salo, Ilmo Leivo
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Cancer
Subjects:
Oral tongue cancer
Early stage
Survival
Tertiary lymphoid structures
Online Access:https://doi.org/10.1186/s12885-022-10208-z

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