Risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture: A case-control study
ObjectivesThe contributing factors for spondylitis after percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) remain unclear. Here, we sought to investigate the factors affecting spondylitis occurrence after PVP/PKP. We also compared the clinical characteristics between patients with...
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| Format: | Article |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.962425/full |
| _version_ | 1828165367784013824 |
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| author | Bo-Wen Zheng Bo-Wen Zheng Bo-Wen Zheng Fu-Sheng Liu Fu-Sheng Liu Bo-Yv Zheng Hua-Qing Niu Jing Li Guo-Hua Lv Ming-Xiang Zou Zhun Xu |
| author_facet | Bo-Wen Zheng Bo-Wen Zheng Bo-Wen Zheng Fu-Sheng Liu Fu-Sheng Liu Bo-Yv Zheng Hua-Qing Niu Jing Li Guo-Hua Lv Ming-Xiang Zou Zhun Xu |
| author_sort | Bo-Wen Zheng |
| collection | DOAJ |
| description | ObjectivesThe contributing factors for spondylitis after percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) remain unclear. Here, we sought to investigate the factors affecting spondylitis occurrence after PVP/PKP. We also compared the clinical characteristics between patients with tuberculous spondylitis (TS) and nontuberculous spondylitis (NTS) following vertebral augmentation.MethodsLiterature searches (from January 1, 1982 to October 16, 2020) using MEDLINE, EMBASE, Google Scholar and Web of science databases were conducted to identify eligible studies according to predefined criteria. The local database was also retrospectively reviewed to include additional TS and NTS patients at our center.ResultsThirty studies from the literature and 11 patients from our local institute were identified, yielding a total of 23 TS patients and 50 NTS patients for analysis. Compared with NTS group, patients in the TS group were more likely to have a history of trauma before PVP/PKP treatment. Univariate analyses of risk factors revealed pulmonary tuberculosis and diabetes were significant factors for TS after PVP/PKP. Analyzing NTS, we found obesity, a history of preoperative trauma, urinary tract infection, diabetes and multiple surgical segments (≥2) were significantly associated with its occurrence following PVP/PKP treatment. Multivariate logistic analyses showed a history of pulmonary tuberculosis and diabetes were independent risk factors for TS after PVP/PKP, while diabetes and the number of surgically treated segments independently influenced NTS development.ConclusionsA history of pulmonary tuberculosis and diabetes were independent risk factors for TS. For NTS, diabetes and the number of surgically treated segments significantly influenced the occurrence of postoperative spinal infection. These data may be helpful for guiding risk stratification and preoperative prevention for patients, thereby reducing the incidence of vertebral osteomyelitis after PVP/PKP. |
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| id | doaj.art-17b04627de5e4633ac6eaf45ebcceb4d |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-12T01:43:32Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Surgery |
| spelling | doaj.art-17b04627de5e4633ac6eaf45ebcceb4d2022-12-22T03:53:08ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-08-01910.3389/fsurg.2022.962425962425Risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture: A case-control studyBo-Wen Zheng0Bo-Wen Zheng1Bo-Wen Zheng2Fu-Sheng Liu3Fu-Sheng Liu4Bo-Yv Zheng5Hua-Qing Niu6Jing Li7Guo-Hua Lv8Ming-Xiang Zou9Zhun Xu10Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, ChinaDepartment of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, ChinaMusculoskeletal Tumor Center, Peking University People’s Hospital, Peking University, Beijing, ChinaDepartment of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, ChinaDepartment of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Orthopedics Surgery, General Hospital of the Central Theater Command, Wuhan, ChinaDepartment of Orthopedics Surgery, General Hospital of the Central Theater Command, Wuhan, ChinaDepartment of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, ChinaDepartment of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, ChinaObjectivesThe contributing factors for spondylitis after percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) remain unclear. Here, we sought to investigate the factors affecting spondylitis occurrence after PVP/PKP. We also compared the clinical characteristics between patients with tuberculous spondylitis (TS) and nontuberculous spondylitis (NTS) following vertebral augmentation.MethodsLiterature searches (from January 1, 1982 to October 16, 2020) using MEDLINE, EMBASE, Google Scholar and Web of science databases were conducted to identify eligible studies according to predefined criteria. The local database was also retrospectively reviewed to include additional TS and NTS patients at our center.ResultsThirty studies from the literature and 11 patients from our local institute were identified, yielding a total of 23 TS patients and 50 NTS patients for analysis. Compared with NTS group, patients in the TS group were more likely to have a history of trauma before PVP/PKP treatment. Univariate analyses of risk factors revealed pulmonary tuberculosis and diabetes were significant factors for TS after PVP/PKP. Analyzing NTS, we found obesity, a history of preoperative trauma, urinary tract infection, diabetes and multiple surgical segments (≥2) were significantly associated with its occurrence following PVP/PKP treatment. Multivariate logistic analyses showed a history of pulmonary tuberculosis and diabetes were independent risk factors for TS after PVP/PKP, while diabetes and the number of surgically treated segments independently influenced NTS development.ConclusionsA history of pulmonary tuberculosis and diabetes were independent risk factors for TS. For NTS, diabetes and the number of surgically treated segments significantly influenced the occurrence of postoperative spinal infection. These data may be helpful for guiding risk stratification and preoperative prevention for patients, thereby reducing the incidence of vertebral osteomyelitis after PVP/PKP.https://www.frontiersin.org/articles/10.3389/fsurg.2022.962425/fullpercutaneous vertebroplastypercutaneous kyphoplastytuberculous spondylitisnontuberculous spondylitispyogenic spondylitisrisk factors |
| spellingShingle | Bo-Wen Zheng Bo-Wen Zheng Bo-Wen Zheng Fu-Sheng Liu Fu-Sheng Liu Bo-Yv Zheng Hua-Qing Niu Jing Li Guo-Hua Lv Ming-Xiang Zou Zhun Xu Risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture: A case-control study Frontiers in Surgery percutaneous vertebroplasty percutaneous kyphoplasty tuberculous spondylitis nontuberculous spondylitis pyogenic spondylitis risk factors |
| title | Risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture: A case-control study |
| title_full | Risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture: A case-control study |
| title_fullStr | Risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture: A case-control study |
| title_full_unstemmed | Risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture: A case-control study |
| title_short | Risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture: A case-control study |
| title_sort | risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture a case control study |
| topic | percutaneous vertebroplasty percutaneous kyphoplasty tuberculous spondylitis nontuberculous spondylitis pyogenic spondylitis risk factors |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.962425/full |
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