Isolated pulmonary embolism following COVID vaccination: 2 case reports and a review of post-acute pulmonary embolism complications and follow-up

Acute pulmonary embolism (PE) is a frequent cause of hypoxemic respiratory failure and presentation to the emergency department. The incidence is on the increase since the COVID-19 outbreak. While COVID infection represents a prothrombotic state, the introduction of COVID vaccines to a lesser extent...

Full description

Bibliographic Details
Main Authors: Nwosu Ifeanyi, Nsofor Chinenye, Oreoluwa Oladiran, Edidiong David, Chiamaka Mmonu, Chinyere Ogbonna-Nwosu
Format: Article
Language:English
Published: Greater Baltimore Medical Center 2021-11-01
Series:Journal of Community Hospital Internal Medicine Perspectives
Subjects:
Online Access:http://dx.doi.org/10.1080/20009666.2021.1990825
_version_ 1828082690594701312
author Nwosu Ifeanyi
Nsofor Chinenye
Oreoluwa Oladiran
Edidiong David
Chiamaka Mmonu
Chinyere Ogbonna-Nwosu
author_facet Nwosu Ifeanyi
Nsofor Chinenye
Oreoluwa Oladiran
Edidiong David
Chiamaka Mmonu
Chinyere Ogbonna-Nwosu
author_sort Nwosu Ifeanyi
collection DOAJ
description Acute pulmonary embolism (PE) is a frequent cause of hypoxemic respiratory failure and presentation to the emergency department. The incidence is on the increase since the COVID-19 outbreak. While COVID infection represents a prothrombotic state, the introduction of COVID vaccines to a lesser extent increased the risk of unprovoked venous thrombus formation and risk of pulmonary embolism. PE is mostly associated with deep vein thrombosis (DVT) and only a few cases of isolated or De novo PE exist in literature. We report two cases of isolated PE associated with COVID-19 vaccinations. We aimed to highlight the need to suspect isolated PE in patients presenting with hypoxemic respiratory failure days to several weeks following COVID-19 vaccination and emphasize the importance of post-discharge follow-up for evaluating chronic thromboembolic pulmonary hypertension (CTEPH).
first_indexed 2024-04-11T03:55:58Z
format Article
id doaj.art-17b20e8551264d70b6b8521352fca0b0
institution Directory Open Access Journal
issn 2000-9666
language English
last_indexed 2024-04-11T03:55:58Z
publishDate 2021-11-01
publisher Greater Baltimore Medical Center
record_format Article
series Journal of Community Hospital Internal Medicine Perspectives
spelling doaj.art-17b20e8551264d70b6b8521352fca0b02023-01-02T00:23:01ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662021-11-0111687787910.1080/20009666.2021.19908251990825Isolated pulmonary embolism following COVID vaccination: 2 case reports and a review of post-acute pulmonary embolism complications and follow-upNwosu Ifeanyi0Nsofor Chinenye1Oreoluwa Oladiran2Edidiong David3Chiamaka Mmonu4Chinyere Ogbonna-Nwosu5Maimonides Medical CentreMilton Keynes University HospitalReading Hospital Tower HealthHarlingen Medical CentreDanferd Specialist ClinicFederal Teaching Hospital AbakalikiAcute pulmonary embolism (PE) is a frequent cause of hypoxemic respiratory failure and presentation to the emergency department. The incidence is on the increase since the COVID-19 outbreak. While COVID infection represents a prothrombotic state, the introduction of COVID vaccines to a lesser extent increased the risk of unprovoked venous thrombus formation and risk of pulmonary embolism. PE is mostly associated with deep vein thrombosis (DVT) and only a few cases of isolated or De novo PE exist in literature. We report two cases of isolated PE associated with COVID-19 vaccinations. We aimed to highlight the need to suspect isolated PE in patients presenting with hypoxemic respiratory failure days to several weeks following COVID-19 vaccination and emphasize the importance of post-discharge follow-up for evaluating chronic thromboembolic pulmonary hypertension (CTEPH).http://dx.doi.org/10.1080/20009666.2021.1990825isolated pulmonary embolismdeep vein thrombosiscovid-19 vaccinechronic thromboembolic pulmonary hypertension
spellingShingle Nwosu Ifeanyi
Nsofor Chinenye
Oreoluwa Oladiran
Edidiong David
Chiamaka Mmonu
Chinyere Ogbonna-Nwosu
Isolated pulmonary embolism following COVID vaccination: 2 case reports and a review of post-acute pulmonary embolism complications and follow-up
Journal of Community Hospital Internal Medicine Perspectives
isolated pulmonary embolism
deep vein thrombosis
covid-19 vaccine
chronic thromboembolic pulmonary hypertension
title Isolated pulmonary embolism following COVID vaccination: 2 case reports and a review of post-acute pulmonary embolism complications and follow-up
title_full Isolated pulmonary embolism following COVID vaccination: 2 case reports and a review of post-acute pulmonary embolism complications and follow-up
title_fullStr Isolated pulmonary embolism following COVID vaccination: 2 case reports and a review of post-acute pulmonary embolism complications and follow-up
title_full_unstemmed Isolated pulmonary embolism following COVID vaccination: 2 case reports and a review of post-acute pulmonary embolism complications and follow-up
title_short Isolated pulmonary embolism following COVID vaccination: 2 case reports and a review of post-acute pulmonary embolism complications and follow-up
title_sort isolated pulmonary embolism following covid vaccination 2 case reports and a review of post acute pulmonary embolism complications and follow up
topic isolated pulmonary embolism
deep vein thrombosis
covid-19 vaccine
chronic thromboembolic pulmonary hypertension
url http://dx.doi.org/10.1080/20009666.2021.1990825
work_keys_str_mv AT nwosuifeanyi isolatedpulmonaryembolismfollowingcovidvaccination2casereportsandareviewofpostacutepulmonaryembolismcomplicationsandfollowup
AT nsoforchinenye isolatedpulmonaryembolismfollowingcovidvaccination2casereportsandareviewofpostacutepulmonaryembolismcomplicationsandfollowup
AT oreoluwaoladiran isolatedpulmonaryembolismfollowingcovidvaccination2casereportsandareviewofpostacutepulmonaryembolismcomplicationsandfollowup
AT edidiongdavid isolatedpulmonaryembolismfollowingcovidvaccination2casereportsandareviewofpostacutepulmonaryembolismcomplicationsandfollowup
AT chiamakammonu isolatedpulmonaryembolismfollowingcovidvaccination2casereportsandareviewofpostacutepulmonaryembolismcomplicationsandfollowup
AT chinyereogbonnanwosu isolatedpulmonaryembolismfollowingcovidvaccination2casereportsandareviewofpostacutepulmonaryembolismcomplicationsandfollowup