Identification and functional characterization of the extremely long allele of the serotonin transporter-linked polymorphic region

Identification and functional characterization of the extremely long allele of the serotonin transporter-linked polymorphic region

Abstract SLC6A4, which encodes the serotonin transporter, has a functional polymorphism called the serotonin transporter-linked polymorphic region (5-HTTLPR). The 5-HTTLPR consists of short (S) and long (L) alleles, each of which has 14 or 16 tandem repeats. In addition, the extralong (XL) and other...

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Main Authors: Tempei Ikegame, Yosuke Hidaka, Yutaka Nakachi, Yui Murata, Risa Watanabe, Hiroko Sugawara, Tatsuro Asai, Emi Kiyota, Takeo Saito, Masashi Ikeda, Tsukasa Sasaki, Mamoru Hashimoto, Tomohisa Ishikawa, Minoru Takebayashi, Nakao Iwata, Chihiro Kakiuchi, Tadafumi Kato, Kiyoto Kasai, Miki Bundo, Kazuya Iwamoto
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01242-9

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