Assessment of the Pupil Size in Emmetropic and Myopic Eyes

Introduction: This study aimed to determine the influence of age and gender on pupil size under different illuminance conditions in emmetropic and myopic healthy eyes using Keratograph 4 topography. Methods: This study investigated 221 eyes of 221 subjects. After complete ocular examination, the und...

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Main Authors: Negareh Yazdani, Nasrin Moghadas Sharif, Maliheh Karimpour, Asieh Ehsaei
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-09-01
Series:Reviews in Clinical Medicine
Subjects:
Online Access:https://rcm.mums.ac.ir/article_16738_4d2eb61fe5574b181e9d3d67fa75e2e1.pdf
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author Negareh Yazdani
Nasrin Moghadas Sharif
Maliheh Karimpour
Asieh Ehsaei
author_facet Negareh Yazdani
Nasrin Moghadas Sharif
Maliheh Karimpour
Asieh Ehsaei
author_sort Negareh Yazdani
collection DOAJ
description Introduction: This study aimed to determine the influence of age and gender on pupil size under different illuminance conditions in emmetropic and myopic healthy eyes using Keratograph 4 topography. Methods: This study investigated 221 eyes of 221 subjects. After complete ocular examination, the undilated pupil diameters were measured using a pupilometer and Keratograph 4 software (OCULUS, Wetzlar, Germany) with a sequence of 9.8 seconds of the scotopic stimulus (0.1 lux) and 0.2 seconds of the photopic stimulus (150 lux) repeated 5 times automatically. At the end of the procedure, the software provided maximum and minimum values (scotopic and photopic) of the pupil diameter. The age, gender, and refraction related changes of the pupil size were evaluated in different illuminance conditions. Results: Out of 221 participants in this study, 122 (85 female) and 99 (66 female) cases were myopes (MSE: -2.18±1.69 D, age: 26.03±6.98 years) and emmetropes (MSE: -0.11±0.27 D, age: 28.05±10.17 years), respectively. Considering refractive groups, pupil size was larger in myopes, compared to the emmetropes in both illuminance conditions (p <0.001). Moreover, the pupil size was found to be independent of gender in both photopic and scotopic conditions (P=0.71 and P=0.55, respectively). Additionally, a significant decrease was observed in pupil size with increasing age (p <0.001). Conclusion: This study showed that pupil size is influenced by age, illumination levels, and refractive status. These findings are important in both the optical industry and clinical decision-making process regarding treatment management.
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spelling doaj.art-17bc9be6992b4099b6520517ec2036202022-12-27T13:03:45ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922020-09-017311011310.22038/rcm.2020.50392.132816738Assessment of the Pupil Size in Emmetropic and Myopic EyesNegareh Yazdani0Nasrin Moghadas Sharif1Maliheh Karimpour2Asieh Ehsaei3Department of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran. Refractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Introduction: This study aimed to determine the influence of age and gender on pupil size under different illuminance conditions in emmetropic and myopic healthy eyes using Keratograph 4 topography. Methods: This study investigated 221 eyes of 221 subjects. After complete ocular examination, the undilated pupil diameters were measured using a pupilometer and Keratograph 4 software (OCULUS, Wetzlar, Germany) with a sequence of 9.8 seconds of the scotopic stimulus (0.1 lux) and 0.2 seconds of the photopic stimulus (150 lux) repeated 5 times automatically. At the end of the procedure, the software provided maximum and minimum values (scotopic and photopic) of the pupil diameter. The age, gender, and refraction related changes of the pupil size were evaluated in different illuminance conditions. Results: Out of 221 participants in this study, 122 (85 female) and 99 (66 female) cases were myopes (MSE: -2.18±1.69 D, age: 26.03±6.98 years) and emmetropes (MSE: -0.11±0.27 D, age: 28.05±10.17 years), respectively. Considering refractive groups, pupil size was larger in myopes, compared to the emmetropes in both illuminance conditions (p <0.001). Moreover, the pupil size was found to be independent of gender in both photopic and scotopic conditions (P=0.71 and P=0.55, respectively). Additionally, a significant decrease was observed in pupil size with increasing age (p <0.001). Conclusion: This study showed that pupil size is influenced by age, illumination levels, and refractive status. These findings are important in both the optical industry and clinical decision-making process regarding treatment management.https://rcm.mums.ac.ir/article_16738_4d2eb61fe5574b181e9d3d67fa75e2e1.pdfpupil sizekeratographagegendermyopiaemmetropia
spellingShingle Negareh Yazdani
Nasrin Moghadas Sharif
Maliheh Karimpour
Asieh Ehsaei
Assessment of the Pupil Size in Emmetropic and Myopic Eyes
Reviews in Clinical Medicine
pupil size
keratograph
age
gender
myopia
emmetropia
title Assessment of the Pupil Size in Emmetropic and Myopic Eyes
title_full Assessment of the Pupil Size in Emmetropic and Myopic Eyes
title_fullStr Assessment of the Pupil Size in Emmetropic and Myopic Eyes
title_full_unstemmed Assessment of the Pupil Size in Emmetropic and Myopic Eyes
title_short Assessment of the Pupil Size in Emmetropic and Myopic Eyes
title_sort assessment of the pupil size in emmetropic and myopic eyes
topic pupil size
keratograph
age
gender
myopia
emmetropia
url https://rcm.mums.ac.ir/article_16738_4d2eb61fe5574b181e9d3d67fa75e2e1.pdf
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AT malihehkarimpour assessmentofthepupilsizeinemmetropicandmyopiceyes
AT asiehehsaei assessmentofthepupilsizeinemmetropicandmyopiceyes