Localised dynactin protects growing microtubules to deliver oskar mRNA to the posterior cortex of the Drosophila oocyte

Localised dynactin protects growing microtubules to deliver oskar mRNA to the posterior cortex of the Drosophila oocyte

The localisation of oskar mRNA to the posterior of the Drosophila oocyte defines where the abdomen and germ cells form in the embryo. Kinesin 1 transports oskar mRNA to the oocyte posterior along a polarised microtubule cytoskeleton that grows from non-centrosomal microtubule organising centres (ncM...

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Detalles Bibliográficos
Main Authors: Ross Nieuwburg, Dmitry Nashchekin, Maximilian Jakobs, Andrew P Carter, Philipp Khuc Trong, Raymond E Goldstein, Daniel St Johnston
Formato: Artigo
Idioma:English
Publicado: eLife Sciences Publications Ltd 2017-10-01
Series:eLife
Subjects:
RNA localisation
cell polarity
microtubules
motor proteins
Acceso en liña:https://elifesciences.org/articles/27237

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