BRAF mutations may identify a clinically distinct subset of glioblastoma
Abstract Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Prior studies examining the mutational landscape of GBM revealed recurrent alterations in genes that regulate the same growth control pathways. To this regard, ~ 40% of GBM harbor EGFR alterations, whereas BRAF v...
Main Authors: | Samantha N. McNulty, Katherine E. Schwetye, Cole Ferguson, Chad E. Storer, George Ansstas, Albert H. Kim, David H. Gutmann, Joshua B. Rubin, Richard D. Head, Sonika Dahiya |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-99278-w |
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