BRAF mutations may identify a clinically distinct subset of glioblastoma

Abstract Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Prior studies examining the mutational landscape of GBM revealed recurrent alterations in genes that regulate the same growth control pathways. To this regard, ~ 40% of GBM harbor EGFR alterations, whereas BRAF v...

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Main Authors: Samantha N. McNulty, Katherine E. Schwetye, Cole Ferguson, Chad E. Storer, George Ansstas, Albert H. Kim, David H. Gutmann, Joshua B. Rubin, Richard D. Head, Sonika Dahiya
格式: 文件
语言:English
出版: Nature Portfolio 2021-10-01
丛编:Scientific Reports
在线阅读:https://doi.org/10.1038/s41598-021-99278-w