Predictive Value of COPD History on In-Stent Restenosis in Coronary Arteries Following Percutaneous Coronary Intervention
Ling Hou,1 Ke Su,2 Jinbo Zhao,2 Yuanhong Li2 1Department of Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Shiyan, Hubei Province, People’s Republic of China; 2Cardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei Univ...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-08-01
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| Series: | International Journal of General Medicine |
| Subjects: | |
| Online Access: | https://www.dovepress.com/predictive-value-of-copd-history-on-in-stent-restenosis-in-coronary-ar-peer-reviewed-fulltext-article-IJGM |
| _version_ | 1797730094109687808 |
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| author | Hou L Su K Zhao J Li Y |
| author_facet | Hou L Su K Zhao J Li Y |
| author_sort | Hou L |
| collection | DOAJ |
| description | Ling Hou,1 Ke Su,2 Jinbo Zhao,2 Yuanhong Li2 1Department of Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Shiyan, Hubei Province, People’s Republic of China; 2Cardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Enshi, Hubei Province, People’s Republic of ChinaCorrespondence: Yuanhong Li, Email lyh0101@vip.comObjective: Chronic obstructive pulmonary disease (COPD) is a prevalent chronic respiratory disease that poses a significant health risk to individuals. Patients with COPD are predisposed to a higher incidence of coronary artery disease (CAD) than the general population. This study aims to investigate the correlation between COPD and the incidence of in-stent restenosis (ISR) after percutaneous coronary intervention (PCI).Methods: This study retrospectively analyzed the clinical data and laboratory test results of patients who underwent PCI at our hospital between January 2018 and December 2021 to investigate the relationship between COPD and drug-Eluting Stents (DES) postoperative ISR. We employed the best subset method to select the most suitable combination of predictive factors, utilizing the data, and verified the precision of the model by means of internal validation. We ultimately assessed the performance of the prediction model using an ROC curve.Results: The research indicates that COPD is an independent risk factor for ISR after PCI (OR=2.437, 95% CI [1.336, 4.495], P=0.004). The analysis revealed an area under the receiver operating characteristic (ROC) curve of 0.783 for the training group and 0.705 for the testing group, indicating a model fitting for both groups (both > 0.5).Conclusion: COPD history is a dependable predictor of stent restenosis post percutaneous coronary intervention.Keywords: percutaneous coronary intervention, PCI, chronic obstructive pulmonary disease, COPD, in-stent restenosis, ISR, drug-eluting stents, DES, optimal subset regression |
| first_indexed | 2024-03-12T11:39:10Z |
| format | Article |
| id | doaj.art-17c1728673f14bf68f47e1fcbb0b4d87 |
| institution | Directory Open Access Journal |
| issn | 1178-7074 |
| language | English |
| last_indexed | 2024-03-12T11:39:10Z |
| publishDate | 2023-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of General Medicine |
| spelling | doaj.art-17c1728673f14bf68f47e1fcbb0b4d872023-08-31T19:08:36ZengDove Medical PressInternational Journal of General Medicine1178-70742023-08-01Volume 163977398486319Predictive Value of COPD History on In-Stent Restenosis in Coronary Arteries Following Percutaneous Coronary InterventionHou LSu KZhao JLi YLing Hou,1 Ke Su,2 Jinbo Zhao,2 Yuanhong Li2 1Department of Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Shiyan, Hubei Province, People’s Republic of China; 2Cardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Enshi, Hubei Province, People’s Republic of ChinaCorrespondence: Yuanhong Li, Email lyh0101@vip.comObjective: Chronic obstructive pulmonary disease (COPD) is a prevalent chronic respiratory disease that poses a significant health risk to individuals. Patients with COPD are predisposed to a higher incidence of coronary artery disease (CAD) than the general population. This study aims to investigate the correlation between COPD and the incidence of in-stent restenosis (ISR) after percutaneous coronary intervention (PCI).Methods: This study retrospectively analyzed the clinical data and laboratory test results of patients who underwent PCI at our hospital between January 2018 and December 2021 to investigate the relationship between COPD and drug-Eluting Stents (DES) postoperative ISR. We employed the best subset method to select the most suitable combination of predictive factors, utilizing the data, and verified the precision of the model by means of internal validation. We ultimately assessed the performance of the prediction model using an ROC curve.Results: The research indicates that COPD is an independent risk factor for ISR after PCI (OR=2.437, 95% CI [1.336, 4.495], P=0.004). The analysis revealed an area under the receiver operating characteristic (ROC) curve of 0.783 for the training group and 0.705 for the testing group, indicating a model fitting for both groups (both > 0.5).Conclusion: COPD history is a dependable predictor of stent restenosis post percutaneous coronary intervention.Keywords: percutaneous coronary intervention, PCI, chronic obstructive pulmonary disease, COPD, in-stent restenosis, ISR, drug-eluting stents, DES, optimal subset regressionhttps://www.dovepress.com/predictive-value-of-copd-history-on-in-stent-restenosis-in-coronary-ar-peer-reviewed-fulltext-article-IJGMpercutaneous coronary interventionpcichronic obstructive pulmonary diseasecopdin-stent restenosisisrdrug-eluting stentsdesoptimal subset regression |
| spellingShingle | Hou L Su K Zhao J Li Y Predictive Value of COPD History on In-Stent Restenosis in Coronary Arteries Following Percutaneous Coronary Intervention International Journal of General Medicine percutaneous coronary intervention pci chronic obstructive pulmonary disease copd in-stent restenosis isr drug-eluting stents des optimal subset regression |
| title | Predictive Value of COPD History on In-Stent Restenosis in Coronary Arteries Following Percutaneous Coronary Intervention |
| title_full | Predictive Value of COPD History on In-Stent Restenosis in Coronary Arteries Following Percutaneous Coronary Intervention |
| title_fullStr | Predictive Value of COPD History on In-Stent Restenosis in Coronary Arteries Following Percutaneous Coronary Intervention |
| title_full_unstemmed | Predictive Value of COPD History on In-Stent Restenosis in Coronary Arteries Following Percutaneous Coronary Intervention |
| title_short | Predictive Value of COPD History on In-Stent Restenosis in Coronary Arteries Following Percutaneous Coronary Intervention |
| title_sort | predictive value of copd history on in stent restenosis in coronary arteries following percutaneous coronary intervention |
| topic | percutaneous coronary intervention pci chronic obstructive pulmonary disease copd in-stent restenosis isr drug-eluting stents des optimal subset regression |
| url | https://www.dovepress.com/predictive-value-of-copd-history-on-in-stent-restenosis-in-coronary-ar-peer-reviewed-fulltext-article-IJGM |
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