New polymethylmethacrylate membrane, NF-U, improves nutritional status and reduces patient-reported symptoms in older dialysis patients
Abstract Introduction We previously reported the nutritional advantage of polymethylmethacrylate (PMMA) membranes to prevent the progression of malnutrition in dialysis patients. In this study, we examined whether a new PMMA dialyzer, NF-U, has advantages to improve the nutritional condition, patien...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-04-01
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| Series: | Renal Replacement Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41100-022-00400-z |
| _version_ | 1819209817655345152 |
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| author | Tetsuro Chida Hiroyuki Igarashi Ikuto Masakane |
| author_facet | Tetsuro Chida Hiroyuki Igarashi Ikuto Masakane |
| author_sort | Tetsuro Chida |
| collection | DOAJ |
| description | Abstract Introduction We previously reported the nutritional advantage of polymethylmethacrylate (PMMA) membranes to prevent the progression of malnutrition in dialysis patients. In this study, we examined whether a new PMMA dialyzer, NF-U, has advantages to improve the nutritional condition, patient-reported symptoms, and other clinical parameters in older dialysis patients. Methods We selected ten older chronic dialysis patients who were treated with NF-U for improving their worsening nutritional parameters and retrospectively evaluated nutrition and patient-reported symptoms. Patient-reported symptoms were surveyed by our original questionnaire including 20 items of symptom. Results Serum albumin concentration, geriatric nutritional risk index, and percent creatinine generation rate increased from 3.01 ± 0.16 to 3.25 ± 0.17 g/dL, 87.7 ± 5.8 to 91.4 ± 6.2, 100.2 ± 21.6 to 111.9 ± 20.9% at 1 and 4 months after switching to NF-U, respectively. For patient-reported outcomes, fatigue and the total score of patient-reported outcomes were improved after switching to NF-U. Conclusion Our results suggest that NF-U is a good choice for older dialysis patients to ameliorate their nutritional status and patient-reported outcomes. |
| first_indexed | 2024-12-23T06:01:19Z |
| format | Article |
| id | doaj.art-17c3053c6a4044db8ca9a15243c1211e |
| institution | Directory Open Access Journal |
| issn | 2059-1381 |
| language | English |
| last_indexed | 2024-12-23T06:01:19Z |
| publishDate | 2022-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Renal Replacement Therapy |
| spelling | doaj.art-17c3053c6a4044db8ca9a15243c1211e2022-12-21T17:57:39ZengBMCRenal Replacement Therapy2059-13812022-04-01811710.1186/s41100-022-00400-zNew polymethylmethacrylate membrane, NF-U, improves nutritional status and reduces patient-reported symptoms in older dialysis patientsTetsuro Chida0Hiroyuki Igarashi1Ikuto Masakane2Yabuki HospitalTendoonsen Yabuki ClinicYabuki HospitalAbstract Introduction We previously reported the nutritional advantage of polymethylmethacrylate (PMMA) membranes to prevent the progression of malnutrition in dialysis patients. In this study, we examined whether a new PMMA dialyzer, NF-U, has advantages to improve the nutritional condition, patient-reported symptoms, and other clinical parameters in older dialysis patients. Methods We selected ten older chronic dialysis patients who were treated with NF-U for improving their worsening nutritional parameters and retrospectively evaluated nutrition and patient-reported symptoms. Patient-reported symptoms were surveyed by our original questionnaire including 20 items of symptom. Results Serum albumin concentration, geriatric nutritional risk index, and percent creatinine generation rate increased from 3.01 ± 0.16 to 3.25 ± 0.17 g/dL, 87.7 ± 5.8 to 91.4 ± 6.2, 100.2 ± 21.6 to 111.9 ± 20.9% at 1 and 4 months after switching to NF-U, respectively. For patient-reported outcomes, fatigue and the total score of patient-reported outcomes were improved after switching to NF-U. Conclusion Our results suggest that NF-U is a good choice for older dialysis patients to ameliorate their nutritional status and patient-reported outcomes.https://doi.org/10.1186/s41100-022-00400-zPolymethylmethacrylateMalnutritionPatient-reported outcomesDialysis-related fatigueOlder dialysis patient |
| spellingShingle | Tetsuro Chida Hiroyuki Igarashi Ikuto Masakane New polymethylmethacrylate membrane, NF-U, improves nutritional status and reduces patient-reported symptoms in older dialysis patients Renal Replacement Therapy Polymethylmethacrylate Malnutrition Patient-reported outcomes Dialysis-related fatigue Older dialysis patient |
| title | New polymethylmethacrylate membrane, NF-U, improves nutritional status and reduces patient-reported symptoms in older dialysis patients |
| title_full | New polymethylmethacrylate membrane, NF-U, improves nutritional status and reduces patient-reported symptoms in older dialysis patients |
| title_fullStr | New polymethylmethacrylate membrane, NF-U, improves nutritional status and reduces patient-reported symptoms in older dialysis patients |
| title_full_unstemmed | New polymethylmethacrylate membrane, NF-U, improves nutritional status and reduces patient-reported symptoms in older dialysis patients |
| title_short | New polymethylmethacrylate membrane, NF-U, improves nutritional status and reduces patient-reported symptoms in older dialysis patients |
| title_sort | new polymethylmethacrylate membrane nf u improves nutritional status and reduces patient reported symptoms in older dialysis patients |
| topic | Polymethylmethacrylate Malnutrition Patient-reported outcomes Dialysis-related fatigue Older dialysis patient |
| url | https://doi.org/10.1186/s41100-022-00400-z |
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