Effect of atrazine and zearalenone on the numer of receptor binding sites for 3H-estradiol in the rat uterus cytosol
The effect of a daily dose of 14 mg atrazine and/or 2.5 mg zearalenone that were administered to rats during 5 days of estrous cycle on the number of receptor binding sites for 3H-estradiol in uterine cytosol was investigated. Comparison with a control group of animals showed no effect of atrazine i...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Czech Academy of Agricultural Sciences
2002-01-01
|
| Series: | Veterinární Medicína |
| Subjects: | |
| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-200201-0003_effect-of-atrazine-and-zearalenone-on-the-numer-of-receptor-binding-sites-for-3h-estradiol-in-the-rat-uterus-cy.php |
| _version_ | 1797897777464737792 |
|---|---|
| author | M. Mitak T. Gojmerac D. Cvrtila Ž. Cvetnič |
| author_facet | M. Mitak T. Gojmerac D. Cvrtila Ž. Cvetnič |
| author_sort | M. Mitak |
| collection | DOAJ |
| description | The effect of a daily dose of 14 mg atrazine and/or 2.5 mg zearalenone that were administered to rats during 5 days of estrous cycle on the number of receptor binding sites for 3H-estradiol in uterine cytosol was investigated. Comparison with a control group of animals showed no effect of atrazine influence on the number of receptor binding sites for 3H-estradiol in the rat uterine cytosol until day 6 of the experiment, when a significantly lower value was recorded (P < 0.05). In the group of animals administered zearalenone, a decline in the number of receptor binding sites for 3H-estradiol in uterine cytosol was observed. On day 4 of the experiment, the number of binding sites was significantly greater (P < 0.05) in this group than in the control group of animals, whereafter it gradually decreased to a significantly lower value (P < 0.05) as compared to the control group on day 6. In the group of animals administered a mixture of atrazine and zearalenone, the number of receptor binding sites for 3H-estradiol in uterine cytosol did not decrease but showed a similar pattern as in the control group of animals, however, at a statistically significantly (P < 0.05) higher level. |
| first_indexed | 2024-04-10T08:02:37Z |
| format | Article |
| id | doaj.art-17c3fbeeac234c2596fa2b7b7b48b36f |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T08:02:37Z |
| publishDate | 2002-01-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-17c3fbeeac234c2596fa2b7b7b48b36f2023-02-23T03:48:59ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922002-01-01471121610.17221/5796-VETMEDvet-200201-0003Effect of atrazine and zearalenone on the numer of receptor binding sites for 3H-estradiol in the rat uterus cytosolM. Mitak0T. Gojmerac1D. Cvrtila2Ž. Cvetnič3Croatian Veterinary Institute, Zagreb, CroatiaCroatian Veterinary Institute, Zagreb, CroatiaCroatian Veterinary Institute, Zagreb, CroatiaCroatian Veterinary Institute, Zagreb, CroatiaThe effect of a daily dose of 14 mg atrazine and/or 2.5 mg zearalenone that were administered to rats during 5 days of estrous cycle on the number of receptor binding sites for 3H-estradiol in uterine cytosol was investigated. Comparison with a control group of animals showed no effect of atrazine influence on the number of receptor binding sites for 3H-estradiol in the rat uterine cytosol until day 6 of the experiment, when a significantly lower value was recorded (P < 0.05). In the group of animals administered zearalenone, a decline in the number of receptor binding sites for 3H-estradiol in uterine cytosol was observed. On day 4 of the experiment, the number of binding sites was significantly greater (P < 0.05) in this group than in the control group of animals, whereafter it gradually decreased to a significantly lower value (P < 0.05) as compared to the control group on day 6. In the group of animals administered a mixture of atrazine and zearalenone, the number of receptor binding sites for 3H-estradiol in uterine cytosol did not decrease but showed a similar pattern as in the control group of animals, however, at a statistically significantly (P < 0.05) higher level.https://vetmed.agriculturejournals.cz/artkey/vet-200201-0003_effect-of-atrazine-and-zearalenone-on-the-numer-of-receptor-binding-sites-for-3h-estradiol-in-the-rat-uterus-cy.phpatrazinezearalenone3h-estradiol receptorovaryuterusrat |
| spellingShingle | M. Mitak T. Gojmerac D. Cvrtila Ž. Cvetnič Effect of atrazine and zearalenone on the numer of receptor binding sites for 3H-estradiol in the rat uterus cytosol Veterinární Medicína atrazine zearalenone 3h-estradiol receptor ovary uterus rat |
| title | Effect of atrazine and zearalenone on the numer of receptor binding sites for 3H-estradiol in the rat uterus cytosol |
| title_full | Effect of atrazine and zearalenone on the numer of receptor binding sites for 3H-estradiol in the rat uterus cytosol |
| title_fullStr | Effect of atrazine and zearalenone on the numer of receptor binding sites for 3H-estradiol in the rat uterus cytosol |
| title_full_unstemmed | Effect of atrazine and zearalenone on the numer of receptor binding sites for 3H-estradiol in the rat uterus cytosol |
| title_short | Effect of atrazine and zearalenone on the numer of receptor binding sites for 3H-estradiol in the rat uterus cytosol |
| title_sort | effect of atrazine and zearalenone on the numer of receptor binding sites for 3h estradiol in the rat uterus cytosol |
| topic | atrazine zearalenone 3h-estradiol receptor ovary uterus rat |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-200201-0003_effect-of-atrazine-and-zearalenone-on-the-numer-of-receptor-binding-sites-for-3h-estradiol-in-the-rat-uterus-cy.php |
| work_keys_str_mv | AT mmitak effectofatrazineandzearalenoneonthenumerofreceptorbindingsitesfor3hestradiolintheratuteruscytosol AT tgojmerac effectofatrazineandzearalenoneonthenumerofreceptorbindingsitesfor3hestradiolintheratuteruscytosol AT dcvrtila effectofatrazineandzearalenoneonthenumerofreceptorbindingsitesfor3hestradiolintheratuteruscytosol AT zcvetnic effectofatrazineandzearalenoneonthenumerofreceptorbindingsitesfor3hestradiolintheratuteruscytosol |