The Antiasthma Medication Ciclesonide Suppresses Breast Cancer Stem Cells through Inhibition of the Glucocorticoid Receptor Signaling-Dependent YAP Pathway

Ciclesonide is an FDA-approved glucocorticoid used to treat asthma and allergic rhinitis. However, whether it has anticancer and anti-cancer stem cell (CSC) effects is unknown. This study focused on investigating the effect of ciclesonide on breast cancer and CSCs and determining its underlying mech...

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Hlavní autoři: Su-Lim Kim, Hack Sun Choi, Ji-Hyang Kim, Dong-Sun Lee
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2020-12-01
Edice:Molecules
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On-line přístup:https://www.mdpi.com/1420-3049/25/24/6028