A Trypsin Inhibitor from <i>Moringa oleifera</i> Flowers Modulates the Immune Response In Vitro of <i>Trypanosoma cruzi</i>-Infected Human Cells

A Trypsin Inhibitor from <i>Moringa oleifera</i> Flowers Modulates the Immune Response In Vitro of <i>Trypanosoma cruzi</i>-Infected Human Cells

<i>Trypanosoma cruzi</i> causes the lethal Chagas disease, which is endemic in Latin America. Flowers of <i>Moringa oleifera</i> (Moringaceae) express a trypsin inhibitor (MoFTI) whose toxicity to <i>T. cruzi</i> trypomastigotes was previously reported. Here, we s...

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Bibliographic Details
Main Authors: Isabella Coimbra Vila Nova, Leyllane Rafael Moreira, Diego José Lira Torres, Kamila Kássia dos Santos Oliveira, Leydianne Leite de Siqueira Patriota, Luana Cassandra Breitenbach Barroso Coelho, Patrícia Maria Guedes Paiva, Thiago Henrique Napoleão, Virgínia Maria Barros de Lorena, Emmanuel Viana Pontual
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antibiotics
Subjects:
cytokines
cytotoxicity
immunomodulatory agent
<i>Moringa oleifera</i>
protease inhibitor
trypanocidal agent
Online Access:https://www.mdpi.com/2079-6382/9/8/515

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