Anti-tuberculosis chemotherapy alters TNFR2 expression on CD4+ lymphocytes in both drug-sensitive and -resistant tuberculosis: however, only drug-resistant tuberculosis maintains a pro-inflammatory profile after a long time

Anti-tuberculosis chemotherapy alters TNFR2 expression on CD4+ lymphocytes in both drug-sensitive and -resistant tuberculosis: however, only drug-resistant tuberculosis maintains a pro-inflammatory profile after a long time

Abstract Background Tuberculosis (TB) is an infectious disease. During TB, regulatory T cells (Treg) are related to poor prognosis. However, information about conventional and unconventional Treg (cTreg and uTreg, respectively) is limited. The tumour necrosis factor (TNF) and its receptors (TNFR1 an...

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Main Authors: Norma A. Téllez-Navarrete, Lucero A. Ramon-Luing, Marcela Muñoz-Torrico, Mario Preciado-García, Karen Medina-Quero, Rogelio Hernandez-Pando, Leslie Chavez-Galan
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Medicine
Subjects:
Tuberculosis
Drug-resistance
Tregs
Receptors
TNF
Online Access:https://doi.org/10.1186/s10020-021-00320-4

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