Risk factors for asthma and allergy associated with urban migration: background and methodology of a cross-sectional study in Afro-Ecuadorian school children in Northeastern Ecuador (Esmeraldas-SCAALA Study)
<p>Abstract</p> <p>Background</p> <p>Asthma and allergic diseases are becoming increasingly frequent in children in urban centres of Latin America although the prevalence of allergic disease is still low in rural areas. Understanding better why the prevalence of asthma...
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Format: | Article |
Language: | English |
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BMC
2006-09-01
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Series: | BMC Pulmonary Medicine |
Online Access: | http://www.biomedcentral.com/1471-2466/6/24 |
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author | Stein Renato T de Carvalho Lain Genser Bernd Alcântara-Neves Neuza M Rodriguez Alejandro Vaca Maritza G Chico Martha E Cooper Philip J Cruz Alvaro A Rodrigues Laura C Barreto Mauricio L |
author_facet | Stein Renato T de Carvalho Lain Genser Bernd Alcântara-Neves Neuza M Rodriguez Alejandro Vaca Maritza G Chico Martha E Cooper Philip J Cruz Alvaro A Rodrigues Laura C Barreto Mauricio L |
author_sort | Stein Renato T |
collection | DOAJ |
description | <p>Abstract</p> <p>Background</p> <p>Asthma and allergic diseases are becoming increasingly frequent in children in urban centres of Latin America although the prevalence of allergic disease is still low in rural areas. Understanding better why the prevalence of asthma is greater in urban migrant populations and the role of risk factors such as life style and environmental exposures, may be key to understand what is behind this trend.</p> <p>Methods/design</p> <p>The Esmeraldas-SCAALA (Social Changes, Asthma and Allergy in Latin America) study consists of cross-sectional and nested case-control studies of school children in rural and urban areas of Esmeraldas Province in Ecuador. The cross-sectional study will investigate risk factors for atopy and allergic disease in rural and migrant urban Afro-Ecuadorian school children and the nested case-control study will examine environmental, biologic and social risk factors for asthma among asthma cases and non-asthmatic controls from the cross-sectional study. Data will be collected through standardised questionnaires, skin prick testing to relevant aeroallergen extracts, stool examinations for parasites, blood sampling (for measurement of IgE, interleukins and other immunological parameters), anthropometric measurements for assessment of nutritional status, exercise testing for assessment of exercise-induced bronchospasm and dust sampling for measurement of household endotoxin and allergen levels.</p> <p>Discussion</p> <p>The information will be used to identify the factors associated with an increased risk of asthma and allergies in migrant and urbanizing populations, to improve the understanding of the causes of the increase in asthma prevalence and to identify potentially modifiable factors to inform the design of prevention programmes to reduce the risk of allergy in urban populations in Latin America.</p> |
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institution | Directory Open Access Journal |
issn | 1471-2466 |
language | English |
last_indexed | 2024-04-13T03:09:29Z |
publishDate | 2006-09-01 |
publisher | BMC |
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series | BMC Pulmonary Medicine |
spelling | doaj.art-17cd88f318794f4490a6d0557ce27af82022-12-22T03:05:07ZengBMCBMC Pulmonary Medicine1471-24662006-09-01612410.1186/1471-2466-6-24Risk factors for asthma and allergy associated with urban migration: background and methodology of a cross-sectional study in Afro-Ecuadorian school children in Northeastern Ecuador (Esmeraldas-SCAALA Study)Stein Renato Tde Carvalho LainGenser BerndAlcântara-Neves Neuza MRodriguez AlejandroVaca Maritza GChico Martha ECooper Philip JCruz Alvaro ARodrigues Laura CBarreto Mauricio L<p>Abstract</p> <p>Background</p> <p>Asthma and allergic diseases are becoming increasingly frequent in children in urban centres of Latin America although the prevalence of allergic disease is still low in rural areas. Understanding better why the prevalence of asthma is greater in urban migrant populations and the role of risk factors such as life style and environmental exposures, may be key to understand what is behind this trend.</p> <p>Methods/design</p> <p>The Esmeraldas-SCAALA (Social Changes, Asthma and Allergy in Latin America) study consists of cross-sectional and nested case-control studies of school children in rural and urban areas of Esmeraldas Province in Ecuador. The cross-sectional study will investigate risk factors for atopy and allergic disease in rural and migrant urban Afro-Ecuadorian school children and the nested case-control study will examine environmental, biologic and social risk factors for asthma among asthma cases and non-asthmatic controls from the cross-sectional study. Data will be collected through standardised questionnaires, skin prick testing to relevant aeroallergen extracts, stool examinations for parasites, blood sampling (for measurement of IgE, interleukins and other immunological parameters), anthropometric measurements for assessment of nutritional status, exercise testing for assessment of exercise-induced bronchospasm and dust sampling for measurement of household endotoxin and allergen levels.</p> <p>Discussion</p> <p>The information will be used to identify the factors associated with an increased risk of asthma and allergies in migrant and urbanizing populations, to improve the understanding of the causes of the increase in asthma prevalence and to identify potentially modifiable factors to inform the design of prevention programmes to reduce the risk of allergy in urban populations in Latin America.</p>http://www.biomedcentral.com/1471-2466/6/24 |
spellingShingle | Stein Renato T de Carvalho Lain Genser Bernd Alcântara-Neves Neuza M Rodriguez Alejandro Vaca Maritza G Chico Martha E Cooper Philip J Cruz Alvaro A Rodrigues Laura C Barreto Mauricio L Risk factors for asthma and allergy associated with urban migration: background and methodology of a cross-sectional study in Afro-Ecuadorian school children in Northeastern Ecuador (Esmeraldas-SCAALA Study) BMC Pulmonary Medicine |
title | Risk factors for asthma and allergy associated with urban migration: background and methodology of a cross-sectional study in Afro-Ecuadorian school children in Northeastern Ecuador (Esmeraldas-SCAALA Study) |
title_full | Risk factors for asthma and allergy associated with urban migration: background and methodology of a cross-sectional study in Afro-Ecuadorian school children in Northeastern Ecuador (Esmeraldas-SCAALA Study) |
title_fullStr | Risk factors for asthma and allergy associated with urban migration: background and methodology of a cross-sectional study in Afro-Ecuadorian school children in Northeastern Ecuador (Esmeraldas-SCAALA Study) |
title_full_unstemmed | Risk factors for asthma and allergy associated with urban migration: background and methodology of a cross-sectional study in Afro-Ecuadorian school children in Northeastern Ecuador (Esmeraldas-SCAALA Study) |
title_short | Risk factors for asthma and allergy associated with urban migration: background and methodology of a cross-sectional study in Afro-Ecuadorian school children in Northeastern Ecuador (Esmeraldas-SCAALA Study) |
title_sort | risk factors for asthma and allergy associated with urban migration background and methodology of a cross sectional study in afro ecuadorian school children in northeastern ecuador esmeraldas scaala study |
url | http://www.biomedcentral.com/1471-2466/6/24 |
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