Taking a Bad Turn: Compromised DNA Damage Response in Leukemia
Genomic integrity is of outmost importance for the survival at the cellular and the organismal level and key to human health. To ensure the integrity of their DNA, cells have evolved maintenance programs collectively known as the DNA damage response. Particularly challenging for genome integrity are...
Main Authors: | Nadine Nilles, Birthe Fahrenkrog |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-05-01
|
Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/6/2/11 |
Similar Items
-
The role of DNA double-strand break repair defects in the pathogenesis of neurodegenerative diseases
by: Jie Xinyu, et al.
Published: (2023-06-01) -
Tanshinone I suppresses hepatocellular carcinoma cells growth through targeting DNA double-strand break repair
by: Zhen Qian, et al.
Published: (2023-12-01) -
Prevalent role of homologous recombination in the repair of specific double-strand breaks in Rhizobium etli
by: Fares Osam Yáñez-Cuna, et al.
Published: (2024-02-01) -
DNA double-strand break genetic variants in patients with premature ovarian insufficiency
by: Xuechun Ding, et al.
Published: (2023-07-01) -
The Chromatin Response to Double-Strand DNA Breaks and Their Repair
by: Radoslav Aleksandrov, et al.
Published: (2020-08-01)