Metformin Use and Risk of All-Cause Mortality and Cardiovascular Events in Patients With Chronic Kidney Disease—A Systematic Review and Meta-Analysis

Metformin Use and Risk of All-Cause Mortality and Cardiovascular Events in Patients With Chronic Kidney Disease—A Systematic Review and Meta-Analysis

BackgroundTo evaluate whether metformin use assuredly alters overall all-cause death in patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD).MethodsPubmed, Web of Science, Embase, and Cochrane Central Register of Controlled Trials were systematically searched from inception...

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Bibliographic Details
Main Authors: Yao Hu, Min Lei, Guibao Ke, Xin Huang, Xuan Peng, Lihui Zhong, Ping Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Endocrinology
Subjects:
metformin and mortality in CKD
cardiovascular events
meta-analysis
type 2 diabetes
chronic kidney disease
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.559446/full

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