The Potential of Anti-Diabetic Rākau Rongoā (Māori Herbal Medicine) to Treat Type 2 Diabetes Mellitus (T2DM) Mate Huka: A Review
T2DM (type 2 diabetes mellitus, or Māori term “mate huka”) is a major long-term health issue in New Zealand particularly among the Māori community. Non-insulin drugs commonly used in New Zealand for the treatment of T2DM have limits to their efficacy as well as side effects, which are of concern for...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2020-06-01
|
| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2020.00935/full |
| _version_ | 1818612814603878400 |
|---|---|
| author | Jonni Hazeline Koia Jonni Hazeline Koia Peter Shepherd |
| author_facet | Jonni Hazeline Koia Jonni Hazeline Koia Peter Shepherd |
| author_sort | Jonni Hazeline Koia |
| collection | DOAJ |
| description | T2DM (type 2 diabetes mellitus, or Māori term “mate huka”) is a major long-term health issue in New Zealand particularly among the Māori community. Non-insulin drugs commonly used in New Zealand for the treatment of T2DM have limits to their efficacy as well as side effects, which are of concern for diabetics. As such, the potential for natural products such as traditional rākau rongoā are of interest for potentially preventing the development of T2DM or improving the treatment of the disease. In particular, anti-diabetic effects have been reported for rākau rongoā such as karamu, kūmarahou, and kawakawa. Natural products have been identified in karamu, kūmarahou, and kawakawa that have documented potential effects on glucose metabolism that could contribute to the anti-diabetic effect of these rākau rongoā. As such, this could provide scientific insight into the mātauranga (traditional knowledge) developed over generations by Māori. However, detailed laboratory based and clinical studies would be required to understand and validate these properties of karamu, kūmarahou, and kawakawa, and to understand how they can be used in T2DM treatment. Social determinants of indigenous health such as language, culture, traditional knowledge, and identity, are important in understanding the relationship Māori have with their land and the mātauranga they developed of the medicinal properties within their rākau rongoā, over many centuries. Interestingly, traditional Māori views towards scientific research using animal models to test rākau rongoā are varied but supportive. Furthermore, cultural issues surrounding Māori mana motuhake (self-determination) of traditional rongoā Māori healing practices and the inequity faced by many kairongoā (rongoā Māori practitioners) and tohunga (healers) compared to mainstream health are a current issue within the New Zealand health system. As such, a cultural holistic approach for T2DM care among Māori would be advantageous. This review will outline the available evidence supporting the anti-diabetic efficacy of karamu, kūmarahou, and kawakawa. Currently though there is a lack of molecular research to understand the mechanisms of this efficacy, as such this review will also outline Te Reo Tipu Research, a kaupapa Māori framework for molecular and genomic research on taonga flora. |
| first_indexed | 2024-12-16T15:52:12Z |
| format | Article |
| id | doaj.art-17d1cb25b0fc41df94c2a8bfb1645137 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-12-16T15:52:12Z |
| publishDate | 2020-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-17d1cb25b0fc41df94c2a8bfb16451372022-12-21T22:25:40ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122020-06-011110.3389/fphar.2020.00935512290The Potential of Anti-Diabetic Rākau Rongoā (Māori Herbal Medicine) to Treat Type 2 Diabetes Mellitus (T2DM) Mate Huka: A ReviewJonni Hazeline Koia0Jonni Hazeline Koia1Peter Shepherd2Division of Health, Engineering, Computers and Science, School of Science, University of Waikato, Hamilton, New ZealandDepartment of Māori Health and Metabolic Disease, Te Reo Tipu Research Centre, Waikato, New ZealandDepartment of Molecular Medicine, University of Auckland, Auckland, New ZealandT2DM (type 2 diabetes mellitus, or Māori term “mate huka”) is a major long-term health issue in New Zealand particularly among the Māori community. Non-insulin drugs commonly used in New Zealand for the treatment of T2DM have limits to their efficacy as well as side effects, which are of concern for diabetics. As such, the potential for natural products such as traditional rākau rongoā are of interest for potentially preventing the development of T2DM or improving the treatment of the disease. In particular, anti-diabetic effects have been reported for rākau rongoā such as karamu, kūmarahou, and kawakawa. Natural products have been identified in karamu, kūmarahou, and kawakawa that have documented potential effects on glucose metabolism that could contribute to the anti-diabetic effect of these rākau rongoā. As such, this could provide scientific insight into the mātauranga (traditional knowledge) developed over generations by Māori. However, detailed laboratory based and clinical studies would be required to understand and validate these properties of karamu, kūmarahou, and kawakawa, and to understand how they can be used in T2DM treatment. Social determinants of indigenous health such as language, culture, traditional knowledge, and identity, are important in understanding the relationship Māori have with their land and the mātauranga they developed of the medicinal properties within their rākau rongoā, over many centuries. Interestingly, traditional Māori views towards scientific research using animal models to test rākau rongoā are varied but supportive. Furthermore, cultural issues surrounding Māori mana motuhake (self-determination) of traditional rongoā Māori healing practices and the inequity faced by many kairongoā (rongoā Māori practitioners) and tohunga (healers) compared to mainstream health are a current issue within the New Zealand health system. As such, a cultural holistic approach for T2DM care among Māori would be advantageous. This review will outline the available evidence supporting the anti-diabetic efficacy of karamu, kūmarahou, and kawakawa. Currently though there is a lack of molecular research to understand the mechanisms of this efficacy, as such this review will also outline Te Reo Tipu Research, a kaupapa Māori framework for molecular and genomic research on taonga flora.https://www.frontiersin.org/article/10.3389/fphar.2020.00935/fulltype 2 diabetes mellitusmate hukaanti-diabetic rākau rongoākūmarahou (Pomaderris kumeraho A.Cunn.)karamu (Coprosma robusta Raoul)kawakawa (Macropiper excelsum G.Forst. Miq.) |
| spellingShingle | Jonni Hazeline Koia Jonni Hazeline Koia Peter Shepherd The Potential of Anti-Diabetic Rākau Rongoā (Māori Herbal Medicine) to Treat Type 2 Diabetes Mellitus (T2DM) Mate Huka: A Review Frontiers in Pharmacology type 2 diabetes mellitus mate huka anti-diabetic rākau rongoā kūmarahou (Pomaderris kumeraho A.Cunn.) karamu (Coprosma robusta Raoul) kawakawa (Macropiper excelsum G.Forst. Miq.) |
| title | The Potential of Anti-Diabetic Rākau Rongoā (Māori Herbal Medicine) to Treat Type 2 Diabetes Mellitus (T2DM) Mate Huka: A Review |
| title_full | The Potential of Anti-Diabetic Rākau Rongoā (Māori Herbal Medicine) to Treat Type 2 Diabetes Mellitus (T2DM) Mate Huka: A Review |
| title_fullStr | The Potential of Anti-Diabetic Rākau Rongoā (Māori Herbal Medicine) to Treat Type 2 Diabetes Mellitus (T2DM) Mate Huka: A Review |
| title_full_unstemmed | The Potential of Anti-Diabetic Rākau Rongoā (Māori Herbal Medicine) to Treat Type 2 Diabetes Mellitus (T2DM) Mate Huka: A Review |
| title_short | The Potential of Anti-Diabetic Rākau Rongoā (Māori Herbal Medicine) to Treat Type 2 Diabetes Mellitus (T2DM) Mate Huka: A Review |
| title_sort | potential of anti diabetic rakau rongoa maori herbal medicine to treat type 2 diabetes mellitus t2dm mate huka a review |
| topic | type 2 diabetes mellitus mate huka anti-diabetic rākau rongoā kūmarahou (Pomaderris kumeraho A.Cunn.) karamu (Coprosma robusta Raoul) kawakawa (Macropiper excelsum G.Forst. Miq.) |
| url | https://www.frontiersin.org/article/10.3389/fphar.2020.00935/full |
| work_keys_str_mv | AT jonnihazelinekoia thepotentialofantidiabeticrakaurongoamaoriherbalmedicinetotreattype2diabetesmellitust2dmmatehukaareview AT jonnihazelinekoia thepotentialofantidiabeticrakaurongoamaoriherbalmedicinetotreattype2diabetesmellitust2dmmatehukaareview AT petershepherd thepotentialofantidiabeticrakaurongoamaoriherbalmedicinetotreattype2diabetesmellitust2dmmatehukaareview AT jonnihazelinekoia potentialofantidiabeticrakaurongoamaoriherbalmedicinetotreattype2diabetesmellitust2dmmatehukaareview AT jonnihazelinekoia potentialofantidiabeticrakaurongoamaoriherbalmedicinetotreattype2diabetesmellitust2dmmatehukaareview AT petershepherd potentialofantidiabeticrakaurongoamaoriherbalmedicinetotreattype2diabetesmellitust2dmmatehukaareview |