Uncovering the potential functions of lymph node metastasis-associated aberrant methylation differentially expressed genes and their association with the immune infiltration and prognosis in bladder urothelial carcinoma

Uncovering the potential functions of lymph node metastasis-associated aberrant methylation differentially expressed genes and their association with the immune infiltration and prognosis in bladder urothelial carcinoma

Background Bladder urothelial carcinoma (BLCA) is a malignant tumor of the urinary system. This study aimed to explore the potential role of lymph node metastasis-associated aberrant methylation differentially expressed genes (DEGs) in BLCA. Methods CHAMP and limma packages were used to identify lym...

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Bibliographic Details
Main Authors: Wenzhi Gao, Jiafeng Zhang, Tai Tian, Zhixin Fu, Liangliang Bai, Yifei Yang, Qiangqiang Wu, Wei Wang, Yuexian Guo
Format: Article
Language:English
Published: PeerJ Inc. 2023-04-01
Series:PeerJ
Subjects:
Bladder urothelial carcinoma
Differentially expressed genes
Methylation
Risk score
Immune cell infiltration
AKAP7
Online Access:https://peerj.com/articles/15284.pdf

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