Soluble immune checkpoint molecules: mechanism of formation, function, role in malignant neoplasms

Soluble immune checkpoint molecules: mechanism of formation, function, role in malignant neoplasms

Immune checkpoints (ICs) represent a broad set of stimulatory and inhibitory signaling pathways playing an important role in regulation of immune responses. Initially, ICs have been considered solely as cell membrane-bound receptor and ligand systems, triggering or blocking immune cell function. Ove...

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Bibliographic Details
Main Authors: T. V. Glazanova, I. E. Pavlova, E. V. Kuzmich, L. N. Bubnova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2025-01-01
Series:Медицинская иммунология
Subjects:
immune checkpoint molecules
soluble
formation mechanism
spd-1
spd-l1
malignant neoplasms
hematological malignancies
Online Access:https://www.mimmun.ru/mimmun/article/view/2965

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