Implications of Tributyrin on Gut Microbiota Shifts Related to Performances of Weaning Piglets
Alternatives to antibiotic treatments are required owing to the ban on the use of these drugs as growth promoters in food animal production. Tributyrin appears to play a role in improving growth performance in pigs, albeit with varying degrees of effectiveness. So far, very little is known about its...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/9/3/584 |
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| author | Francesco Miragoli Vania Patrone Aldo Prandini Samantha Sigolo Matteo Dell’Anno Luciana Rossi Alice Senizza Lorenzo Morelli Maria Luisa Callegari |
| author_facet | Francesco Miragoli Vania Patrone Aldo Prandini Samantha Sigolo Matteo Dell’Anno Luciana Rossi Alice Senizza Lorenzo Morelli Maria Luisa Callegari |
| author_sort | Francesco Miragoli |
| collection | DOAJ |
| description | Alternatives to antibiotic treatments are required owing to the ban on the use of these drugs as growth promoters in food animal production. Tributyrin appears to play a role in improving growth performance in pigs, albeit with varying degrees of effectiveness. So far, very little is known about its effects on gut microbiota composition. In this study, we investigated the gut microbiota changes of piglets receiving, at weaning, 0.2% tributyrin added to their basal diet. Microbiota composition was assessed through 16S-rRNA gene sequencing on stools collected from tributyrin and control groups. The functional profiles of microbial communities were predicted from amplicon abundance data. A comparison between dietary groups revealed that tributyrin strongly modulated gut microbiota composition in piglets, increasing the relative abundance of a number of bacterial genera such as <i>Oscillospira</i>, <i>Oscillibacter</i>, <i>Mucispirillum</i> and <i>Butyrivibrio</i>. These genera were positively correlated to animal average daily gain (ADG) and/or body weight (BW). Based on the function profile prediction, the gut microbiome of the tributyrin group possessed an enhanced potential for energy metabolism and a reduced potential for carbohydrate metabolism. In conclusion, our results indicated that tributyrin can promote changes to gut microbial communities, which could contribute to improving animal performance after weaning. |
| first_indexed | 2024-03-10T13:18:04Z |
| format | Article |
| id | doaj.art-17e8f02eb13140faad6f06549aa9efa7 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T13:18:04Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-17e8f02eb13140faad6f06549aa9efa72023-11-21T10:13:48ZengMDPI AGMicroorganisms2076-26072021-03-019358410.3390/microorganisms9030584Implications of Tributyrin on Gut Microbiota Shifts Related to Performances of Weaning PigletsFrancesco Miragoli0Vania Patrone1Aldo Prandini2Samantha Sigolo3Matteo Dell’Anno4Luciana Rossi5Alice Senizza6Lorenzo Morelli7Maria Luisa Callegari8Department for Sustainable Food Process (DiSTAS), Università Cattolica del Sacro Cuore, via E. Parmense 84, 29122 Piacenza, ItalyDepartment for Sustainable Food Process (DiSTAS), Università Cattolica del Sacro Cuore, via E. Parmense 84, 29122 Piacenza, ItalyDepartment of Animal Science, Food and Nutrition (DIANA), Università Cattolica del Sacro Cuore, via E. Parmense 84, 29122 Piacenza, ItalyDepartment of Animal Science, Food and Nutrition (DIANA), Università Cattolica del Sacro Cuore, via E. Parmense 84, 29122 Piacenza, ItalyDepartment of Health, Animal Science and Food Safety, Università degli Studi di Milano, via Trentacoste 2, 20134 Milano, ItalyDepartment of Health, Animal Science and Food Safety, Università degli Studi di Milano, via Trentacoste 2, 20134 Milano, ItalyDepartment for Sustainable Food Process (DiSTAS), Università Cattolica del Sacro Cuore, via E. Parmense 84, 29122 Piacenza, ItalyDepartment for Sustainable Food Process (DiSTAS), Università Cattolica del Sacro Cuore, via E. Parmense 84, 29122 Piacenza, ItalyDepartment for Sustainable Food Process (DiSTAS), Università Cattolica del Sacro Cuore, via E. Parmense 84, 29122 Piacenza, ItalyAlternatives to antibiotic treatments are required owing to the ban on the use of these drugs as growth promoters in food animal production. Tributyrin appears to play a role in improving growth performance in pigs, albeit with varying degrees of effectiveness. So far, very little is known about its effects on gut microbiota composition. In this study, we investigated the gut microbiota changes of piglets receiving, at weaning, 0.2% tributyrin added to their basal diet. Microbiota composition was assessed through 16S-rRNA gene sequencing on stools collected from tributyrin and control groups. The functional profiles of microbial communities were predicted from amplicon abundance data. A comparison between dietary groups revealed that tributyrin strongly modulated gut microbiota composition in piglets, increasing the relative abundance of a number of bacterial genera such as <i>Oscillospira</i>, <i>Oscillibacter</i>, <i>Mucispirillum</i> and <i>Butyrivibrio</i>. These genera were positively correlated to animal average daily gain (ADG) and/or body weight (BW). Based on the function profile prediction, the gut microbiome of the tributyrin group possessed an enhanced potential for energy metabolism and a reduced potential for carbohydrate metabolism. In conclusion, our results indicated that tributyrin can promote changes to gut microbial communities, which could contribute to improving animal performance after weaning.https://www.mdpi.com/2076-2607/9/3/584weaningpigletsgut microbiotatributyrinanimal performance |
| spellingShingle | Francesco Miragoli Vania Patrone Aldo Prandini Samantha Sigolo Matteo Dell’Anno Luciana Rossi Alice Senizza Lorenzo Morelli Maria Luisa Callegari Implications of Tributyrin on Gut Microbiota Shifts Related to Performances of Weaning Piglets Microorganisms weaning piglets gut microbiota tributyrin animal performance |
| title | Implications of Tributyrin on Gut Microbiota Shifts Related to Performances of Weaning Piglets |
| title_full | Implications of Tributyrin on Gut Microbiota Shifts Related to Performances of Weaning Piglets |
| title_fullStr | Implications of Tributyrin on Gut Microbiota Shifts Related to Performances of Weaning Piglets |
| title_full_unstemmed | Implications of Tributyrin on Gut Microbiota Shifts Related to Performances of Weaning Piglets |
| title_short | Implications of Tributyrin on Gut Microbiota Shifts Related to Performances of Weaning Piglets |
| title_sort | implications of tributyrin on gut microbiota shifts related to performances of weaning piglets |
| topic | weaning piglets gut microbiota tributyrin animal performance |
| url | https://www.mdpi.com/2076-2607/9/3/584 |
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