Seed Extract of Psoralea corylifolia and Its Constituent Bakuchiol Impairs AHL-Based Quorum Sensing and Biofilm Formation in Food- and Human-Related Pathogens

Seed Extract of Psoralea corylifolia and Its Constituent Bakuchiol Impairs AHL-Based Quorum Sensing and Biofilm Formation in Food- and Human-Related Pathogens

The emergence of multi-drug resistance in pathogenic bacteria in clinical settings as well as food-borne infections has become a serious health concern. The problem of drug resistance necessitates the need for alternative novel therapeutic strategies to combat this menace. One such approach is targe...

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Bibliographic Details
Main Authors: Fohad Mabood Husain, Iqbal Ahmad, Faez Iqbal Khan, Nasser A. Al-Shabib, Mohammad Hassan Baig, Afzal Hussain, Md Tabish Rehman, Mohamed F. Alajmi, Kevin A. Lobb
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Psoralea corylifolia
bakuchiol
quorum sensing
biofilm
molecular dynamics simulation
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00351/full

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