Phototherapy combined with systemic agents for mycosis fungoides

The choice of tactics for managing a patient with mycosis fungoides is determined by the stage of the disease. In the early stages of mycosis fungoides, a treatment approach using external therapy and various ultraviolet irradiation spectra (UVB-311 nm and PUVA therapy) is preferable. With insuffici...

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Main Authors: Anastasiia A. Vorontsova, Arfenya E. Karamova
Format: Article
Language:English
Published: State Scientific Center of Dermatovenereology and Cosmetology 2023-01-01
Series:Vestnik Dermatologii i Venerologii
Subjects:
Online Access:https://vestnikdv.ru/jour/article/viewFile/1389/pdf
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author Anastasiia A. Vorontsova
Arfenya E. Karamova
author_facet Anastasiia A. Vorontsova
Arfenya E. Karamova
author_sort Anastasiia A. Vorontsova
collection DOAJ
description The choice of tactics for managing a patient with mycosis fungoides is determined by the stage of the disease. In the early stages of mycosis fungoides, a treatment approach using external therapy and various ultraviolet irradiation spectra (UVB-311 nm and PUVA therapy) is preferable. With insufficient efficiency and / or short remissions in some patients, it is possible to use combined methods in the early stages: PUVA therapy or UVB-311 nm therapy. in combination with systemic therapy, including interferon (IFN) 2b preparations, methotrexate and retinoids. The results of original studies demonstrate an increase in the overall response rate when combining PUVA therapy with IFN- or retinoids in patients with stages IB-IIB. The effectiveness of combined treatment regimens using UVB-311 nm remains insufficiently studied.
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spelling doaj.art-17eb5af51ee14bada87f4098794ca5e92023-09-03T12:32:42ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942023-01-01986556410.25208/vdv13891198Phototherapy combined with systemic agents for mycosis fungoidesAnastasiia A. Vorontsova0https://orcid.org/0000-0002-3129-0050Arfenya E. Karamova1https://orcid.org/0000-0003-3805-8489State Research Center of Dermatovenereology and CosmetologyState Research Center of Dermatovenereology and CosmetologyThe choice of tactics for managing a patient with mycosis fungoides is determined by the stage of the disease. In the early stages of mycosis fungoides, a treatment approach using external therapy and various ultraviolet irradiation spectra (UVB-311 nm and PUVA therapy) is preferable. With insufficient efficiency and / or short remissions in some patients, it is possible to use combined methods in the early stages: PUVA therapy or UVB-311 nm therapy. in combination with systemic therapy, including interferon (IFN) 2b preparations, methotrexate and retinoids. The results of original studies demonstrate an increase in the overall response rate when combining PUVA therapy with IFN- or retinoids in patients with stages IB-IIB. The effectiveness of combined treatment regimens using UVB-311 nm remains insufficiently studied.https://vestnikdv.ru/jour/article/viewFile/1389/pdfmycosis fungoidesphototherapyinterferonmethotrexate
spellingShingle Anastasiia A. Vorontsova
Arfenya E. Karamova
Phototherapy combined with systemic agents for mycosis fungoides
Vestnik Dermatologii i Venerologii
mycosis fungoides
phototherapy
interferon
methotrexate
title Phototherapy combined with systemic agents for mycosis fungoides
title_full Phototherapy combined with systemic agents for mycosis fungoides
title_fullStr Phototherapy combined with systemic agents for mycosis fungoides
title_full_unstemmed Phototherapy combined with systemic agents for mycosis fungoides
title_short Phototherapy combined with systemic agents for mycosis fungoides
title_sort phototherapy combined with systemic agents for mycosis fungoides
topic mycosis fungoides
phototherapy
interferon
methotrexate
url https://vestnikdv.ru/jour/article/viewFile/1389/pdf
work_keys_str_mv AT anastasiiaavorontsova phototherapycombinedwithsystemicagentsformycosisfungoides
AT arfenyaekaramova phototherapycombinedwithsystemicagentsformycosisfungoides