Lupus Nephritis With Mild Asymptomatic Hypercalcemia in Children: A Case Report and Literature Review

Lupus nephritis (LN) in Children is caused by Kidney involvement in systemic lupus erythematosus (SLE). SLE is a chronic, multi-systemic, paroxysmal autoimmune disease with a wide spectrum of autoantibodies. Hypercalcemia is a common manifestation of primary hyperparathyroidism and other malignant t...

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Main Authors: Lingling Xu, Jun Zhang, Ronghui Pu, Zhihui Yue, Ying Mo, Xiaoyun Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fped.2019.00507/full
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author Lingling Xu
Jun Zhang
Ronghui Pu
Zhihui Yue
Ying Mo
Xiaoyun Jiang
author_facet Lingling Xu
Jun Zhang
Ronghui Pu
Zhihui Yue
Ying Mo
Xiaoyun Jiang
author_sort Lingling Xu
collection DOAJ
description Lupus nephritis (LN) in Children is caused by Kidney involvement in systemic lupus erythematosus (SLE). SLE is a chronic, multi-systemic, paroxysmal autoimmune disease with a wide spectrum of autoantibodies. Hypercalcemia is a common manifestation of primary hyperparathyroidism and other malignant tumors. LN or SLE with hypercalcemia is rare. We report a case of LN with hypercalcemia and review the literature. It suggests that the pathogenesis of SLE complicated with hypercalcemia complicates the response of drug therapy.
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spelling doaj.art-17ece269bf1a42a3a4c8ab634f0f050f2022-12-22T01:24:46ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602019-12-01710.3389/fped.2019.00507494490Lupus Nephritis With Mild Asymptomatic Hypercalcemia in Children: A Case Report and Literature ReviewLingling XuJun ZhangRonghui PuZhihui YueYing MoXiaoyun JiangLupus nephritis (LN) in Children is caused by Kidney involvement in systemic lupus erythematosus (SLE). SLE is a chronic, multi-systemic, paroxysmal autoimmune disease with a wide spectrum of autoantibodies. Hypercalcemia is a common manifestation of primary hyperparathyroidism and other malignant tumors. LN or SLE with hypercalcemia is rare. We report a case of LN with hypercalcemia and review the literature. It suggests that the pathogenesis of SLE complicated with hypercalcemia complicates the response of drug therapy.https://www.frontiersin.org/article/10.3389/fped.2019.00507/fulllupus nephritissystemic lupus erythematosushypercalcemiachildrencalcium sensing receptor
spellingShingle Lingling Xu
Jun Zhang
Ronghui Pu
Zhihui Yue
Ying Mo
Xiaoyun Jiang
Lupus Nephritis With Mild Asymptomatic Hypercalcemia in Children: A Case Report and Literature Review
Frontiers in Pediatrics
lupus nephritis
systemic lupus erythematosus
hypercalcemia
children
calcium sensing receptor
title Lupus Nephritis With Mild Asymptomatic Hypercalcemia in Children: A Case Report and Literature Review
title_full Lupus Nephritis With Mild Asymptomatic Hypercalcemia in Children: A Case Report and Literature Review
title_fullStr Lupus Nephritis With Mild Asymptomatic Hypercalcemia in Children: A Case Report and Literature Review
title_full_unstemmed Lupus Nephritis With Mild Asymptomatic Hypercalcemia in Children: A Case Report and Literature Review
title_short Lupus Nephritis With Mild Asymptomatic Hypercalcemia in Children: A Case Report and Literature Review
title_sort lupus nephritis with mild asymptomatic hypercalcemia in children a case report and literature review
topic lupus nephritis
systemic lupus erythematosus
hypercalcemia
children
calcium sensing receptor
url https://www.frontiersin.org/article/10.3389/fped.2019.00507/full
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