Relation between serum vitamin B<sub>12</sub> level and duration of treatment with carbamazepine in epilepsy patients
Vitamin B12 levels in the serum of 58 epileptic patients receiving only carbamazepine for at least 6 months were measured. Same number of epilepsy patients with no history of taking antiepileptic medicine were taken as control. The mean level of vitamin B12 in carbamazepine-treated epileptic patient...
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| Format: | Article |
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Bangabandhu Sheikh Mujib Medical University
2016-12-01
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| Series: | Bangabandhu Sheikh Mujib Medical University Journal |
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| Online Access: | https://www.banglajol.info/index.php/BSMMUJ/article/view/30371 |
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| author | Mohammad Tariqul Islam Khair M. Sobhan Mahjabin Rahman Shawly Shafiqur Saleheen Mohammad Masum Emran M. A. Hannan |
| author_facet | Mohammad Tariqul Islam Khair M. Sobhan Mahjabin Rahman Shawly Shafiqur Saleheen Mohammad Masum Emran M. A. Hannan |
| author_sort | Mohammad Tariqul Islam |
| collection | DOAJ |
| description | Vitamin B12 levels in the serum of 58 epileptic patients receiving only carbamazepine for at least 6 months were measured. Same number of epilepsy patients with no history of taking antiepileptic medicine were taken as control. The mean level of vitamin B12 in carbamazepine-treated epileptic patients was 265.5 pg/mL whereas it was 478.3 pg/mL in control. Increased duration of treatment of carbamazepine in epilepsy caused significantly decreased level of serum vitamin B12 (Pearson correlation coefficient, r = -0.9, p<0.0001). In conclusion, serum vitamin B12 level significantly decreased in relation to duration of carbamazepine treatment in epileptic patients. |
| first_indexed | 2024-12-12T10:53:48Z |
| format | Article |
| id | doaj.art-17eedbeb8a8a438abf85b261267f3efd |
| institution | Directory Open Access Journal |
| issn | 2074-2908 2224-7750 |
| language | English |
| last_indexed | 2024-12-12T10:53:48Z |
| publishDate | 2016-12-01 |
| publisher | Bangabandhu Sheikh Mujib Medical University |
| record_format | Article |
| series | Bangabandhu Sheikh Mujib Medical University Journal |
| spelling | doaj.art-17eedbeb8a8a438abf85b261267f3efd2022-12-22T00:26:42ZengBangabandhu Sheikh Mujib Medical UniversityBangabandhu Sheikh Mujib Medical University Journal2074-29082224-77502016-12-019410.3329/bsmmuj.v9i4.3037119594Relation between serum vitamin B<sub>12</sub> level and duration of treatment with carbamazepine in epilepsy patientsMohammad Tariqul Islam0Khair M. Sobhan1Mahjabin Rahman Shawly2Shafiqur Saleheen3Mohammad Masum Emran4M. A. Hannan5Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, DhakaDepartment of Neurology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, BangladeshDepartment of Physical Medicine and Rehabilitation, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, DhakaDepartment of Neurology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, BangladeshDepartment of Neurology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, BangladeshDepartment of Neurology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, BangladeshVitamin B12 levels in the serum of 58 epileptic patients receiving only carbamazepine for at least 6 months were measured. Same number of epilepsy patients with no history of taking antiepileptic medicine were taken as control. The mean level of vitamin B12 in carbamazepine-treated epileptic patients was 265.5 pg/mL whereas it was 478.3 pg/mL in control. Increased duration of treatment of carbamazepine in epilepsy caused significantly decreased level of serum vitamin B12 (Pearson correlation coefficient, r = -0.9, p<0.0001). In conclusion, serum vitamin B12 level significantly decreased in relation to duration of carbamazepine treatment in epileptic patients.https://www.banglajol.info/index.php/BSMMUJ/article/view/30371CarbamazepineEpilepsyVitamin B12 |
| spellingShingle | Mohammad Tariqul Islam Khair M. Sobhan Mahjabin Rahman Shawly Shafiqur Saleheen Mohammad Masum Emran M. A. Hannan Relation between serum vitamin B<sub>12</sub> level and duration of treatment with carbamazepine in epilepsy patients Bangabandhu Sheikh Mujib Medical University Journal Carbamazepine Epilepsy Vitamin B12 |
| title | Relation between serum vitamin B<sub>12</sub> level and duration of treatment with carbamazepine in epilepsy patients |
| title_full | Relation between serum vitamin B<sub>12</sub> level and duration of treatment with carbamazepine in epilepsy patients |
| title_fullStr | Relation between serum vitamin B<sub>12</sub> level and duration of treatment with carbamazepine in epilepsy patients |
| title_full_unstemmed | Relation between serum vitamin B<sub>12</sub> level and duration of treatment with carbamazepine in epilepsy patients |
| title_short | Relation between serum vitamin B<sub>12</sub> level and duration of treatment with carbamazepine in epilepsy patients |
| title_sort | relation between serum vitamin b sub 12 sub level and duration of treatment with carbamazepine in epilepsy patients |
| topic | Carbamazepine Epilepsy Vitamin B12 |
| url | https://www.banglajol.info/index.php/BSMMUJ/article/view/30371 |
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