A Boron Delivery Antibody (BDA) with Boronated Specific Residues: New Perspectives in Boron Neutron Capture Therapy from an In Silico Investigation

A Boron Delivery Antibody (BDA) with Boronated Specific Residues: New Perspectives in Boron Neutron Capture Therapy from an In Silico Investigation

Boron Neutron Capture Therapy (BNCT) is a tumor cell-selective radiotherapy based on a nuclear reaction that occurs when the isotope boron-10 (<sup>10</sup>B) is radiated by low-energy thermal neutrons or epithermal neutrons, triggering a nuclear fission response and enabling a selective...

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Bibliographic Details
Main Authors: Alessandro Rondina, Paola Fossa, Alessandro Orro, Luciano Milanesi, Antonella De Palma, Davide Perico, Pier Luigi Mauri, Pasqualina D’Ursi
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
Boron Neutron Capture Therapy
4-borono-L-phenylalanine
Boron Delivery Antibody strategy
docking
molecular dynamics
Online Access:https://www.mdpi.com/2073-4409/10/11/3225

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