Respiratory Distress and the Bacteria Causing Infection in the Neonates
An analysis of 64 samples of (blood, vagina, anaus) from pregnant mothers and their neonates, only 58 samples showed these types of bacteria Streptococcus agalactiae(GBS), Staphylococcus aureus and Escherichia coli, distributed as: 16 blood isolates from mothers and 25 from neonates, while 13 vagin...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
College of Pharmacy / Mustansiriyah University
2012-06-01
|
| Series: | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/248 |
| _version_ | 1797223838736449536 |
|---|---|
| author | Neihaya Heikmat Zaki |
| author_facet | Neihaya Heikmat Zaki |
| author_sort | Neihaya Heikmat Zaki |
| collection | DOAJ |
| description |
An analysis of 64 samples of (blood, vagina, anaus) from pregnant mothers and their neonates, only 58 samples showed these types of bacteria Streptococcus agalactiae(GBS), Staphylococcus aureus and Escherichia coli, distributed as: 16 blood isolates from mothers and 25 from neonates, while 13 vaginal isolates from mothers and 4 anal isolates from neonates. Bacterial components (phospholipids-PL) purified by High Performance Liquid Chromatography (HPLC), and identified as Cardiolipin (CL) with retention time (10.76 min.), Phosphatidylserine (PS) (8.1min.), and Phosphatidyl ethanolamine (PE) (5.9 min.) compared with standard PL. GBS isolates produced more extracellular phospholipids than other types in this
study.
The three types of bacteria differed in their levels of virulence when injected intratracheally in to a neonatal rabbit model to determine whether they induced pulmonary hypertension in it. After 8 days the rates of surviving neonatal rabbits were 2/15 (13.33%) to GBS, 5/15 to E.coli (33.33%), and 7/15 (46.66%) to S.aureus. The recognition that bacterial phospholipids may cause respiratory distress in newborns with these kinds of bacteria opens new avenues for therapeutic intervention.
|
| first_indexed | 2024-04-24T13:43:35Z |
| format | Article |
| id | doaj.art-17f1b41503474274980e49f3836a1398 |
| institution | Directory Open Access Journal |
| issn | 1815-0993 2959-183X |
| language | English |
| last_indexed | 2024-04-24T13:43:35Z |
| publishDate | 2012-06-01 |
| publisher | College of Pharmacy / Mustansiriyah University |
| record_format | Article |
| series | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| spelling | doaj.art-17f1b41503474274980e49f3836a13982024-04-04T06:58:49ZengCollege of Pharmacy / Mustansiriyah UniversityAl-Mustansiriyah Journal of Pharmaceutical Sciences1815-09932959-183X2012-06-0111110.32947/ajps.v11i1.248Respiratory Distress and the Bacteria Causing Infection in the NeonatesNeihaya Heikmat Zaki0Department of Biology, College of Science, University of Al- Mustansiriya An analysis of 64 samples of (blood, vagina, anaus) from pregnant mothers and their neonates, only 58 samples showed these types of bacteria Streptococcus agalactiae(GBS), Staphylococcus aureus and Escherichia coli, distributed as: 16 blood isolates from mothers and 25 from neonates, while 13 vaginal isolates from mothers and 4 anal isolates from neonates. Bacterial components (phospholipids-PL) purified by High Performance Liquid Chromatography (HPLC), and identified as Cardiolipin (CL) with retention time (10.76 min.), Phosphatidylserine (PS) (8.1min.), and Phosphatidyl ethanolamine (PE) (5.9 min.) compared with standard PL. GBS isolates produced more extracellular phospholipids than other types in this study. The three types of bacteria differed in their levels of virulence when injected intratracheally in to a neonatal rabbit model to determine whether they induced pulmonary hypertension in it. After 8 days the rates of surviving neonatal rabbits were 2/15 (13.33%) to GBS, 5/15 to E.coli (33.33%), and 7/15 (46.66%) to S.aureus. The recognition that bacterial phospholipids may cause respiratory distress in newborns with these kinds of bacteria opens new avenues for therapeutic intervention. https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/248Respiratory Distress, Streptococcus agalactiae, E.coli, Neonates Staphylococcus aureus |
| spellingShingle | Neihaya Heikmat Zaki Respiratory Distress and the Bacteria Causing Infection in the Neonates Al-Mustansiriyah Journal of Pharmaceutical Sciences Respiratory Distress, Streptococcus agalactiae, E.coli, Neonates Staphylococcus aureus |
| title | Respiratory Distress and the Bacteria Causing Infection in the Neonates |
| title_full | Respiratory Distress and the Bacteria Causing Infection in the Neonates |
| title_fullStr | Respiratory Distress and the Bacteria Causing Infection in the Neonates |
| title_full_unstemmed | Respiratory Distress and the Bacteria Causing Infection in the Neonates |
| title_short | Respiratory Distress and the Bacteria Causing Infection in the Neonates |
| title_sort | respiratory distress and the bacteria causing infection in the neonates |
| topic | Respiratory Distress, Streptococcus agalactiae, E.coli, Neonates Staphylococcus aureus |
| url | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/248 |
| work_keys_str_mv | AT neihayaheikmatzaki respiratorydistressandthebacteriacausinginfectionintheneonates |