Orofacial granulomatosis: A disease or a concealed warning.??

Granulomatosis is any condition characterized by the formation of multiple nodules or granulomas in the soft tissues. Differential diagnosis for orofacial region includes a wide spectrum of diseases, but most of these lesions present histopathologically as noncaseating granulomas, giving a nonspecif...

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Main Authors: Priya Anil Bhagde, Jyoti D Bhavthankar, Mandakini Mandale
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2017;volume=60;issue=4;spage=556;epage=559;aulast=Bhagde
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author Priya Anil Bhagde
Jyoti D Bhavthankar
Mandakini Mandale
author_facet Priya Anil Bhagde
Jyoti D Bhavthankar
Mandakini Mandale
author_sort Priya Anil Bhagde
collection DOAJ
description Granulomatosis is any condition characterized by the formation of multiple nodules or granulomas in the soft tissues. Differential diagnosis for orofacial region includes a wide spectrum of diseases, but most of these lesions present histopathologically as noncaseating granulomas, giving a nonspecific depiction and leading to a diagnostic impasse. In the absence of any diagnosable entity, the disease is labelled as “orofacial granulomatosis”. A nine-year-old girl child reported with recurrent gingival enlargement and persistent macrochelia which histopathologically presented as noncaseating granulomas. The disease was progressive raising the suspicion of being oral manifestation of a systemic disorder such as Sarcoidosis or Crohn's disease. This paper throws some light on this rare entity and reports rarer features of this disease, like eye involvement and staphylococcal mucositis in the case report.
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spelling doaj.art-17f4f47f8b624ce7aa33ba3fa446c5812022-12-22T03:12:23ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292017-01-0160455655910.4103/IJPM.IJPM_401_17Orofacial granulomatosis: A disease or a concealed warning.??Priya Anil BhagdeJyoti D BhavthankarMandakini MandaleGranulomatosis is any condition characterized by the formation of multiple nodules or granulomas in the soft tissues. Differential diagnosis for orofacial region includes a wide spectrum of diseases, but most of these lesions present histopathologically as noncaseating granulomas, giving a nonspecific depiction and leading to a diagnostic impasse. In the absence of any diagnosable entity, the disease is labelled as “orofacial granulomatosis”. A nine-year-old girl child reported with recurrent gingival enlargement and persistent macrochelia which histopathologically presented as noncaseating granulomas. The disease was progressive raising the suspicion of being oral manifestation of a systemic disorder such as Sarcoidosis or Crohn's disease. This paper throws some light on this rare entity and reports rarer features of this disease, like eye involvement and staphylococcal mucositis in the case report.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2017;volume=60;issue=4;spage=556;epage=559;aulast=BhagdeCrohn's diseaseorofacial granulomatosissarcoidosis
spellingShingle Priya Anil Bhagde
Jyoti D Bhavthankar
Mandakini Mandale
Orofacial granulomatosis: A disease or a concealed warning.??
Indian Journal of Pathology and Microbiology
Crohn's disease
orofacial granulomatosis
sarcoidosis
title Orofacial granulomatosis: A disease or a concealed warning.??
title_full Orofacial granulomatosis: A disease or a concealed warning.??
title_fullStr Orofacial granulomatosis: A disease or a concealed warning.??
title_full_unstemmed Orofacial granulomatosis: A disease or a concealed warning.??
title_short Orofacial granulomatosis: A disease or a concealed warning.??
title_sort orofacial granulomatosis a disease or a concealed warning
topic Crohn's disease
orofacial granulomatosis
sarcoidosis
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2017;volume=60;issue=4;spage=556;epage=559;aulast=Bhagde
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AT jyotidbhavthankar orofacialgranulomatosisadiseaseoraconcealedwarning
AT mandakinimandale orofacialgranulomatosisadiseaseoraconcealedwarning