Orofacial granulomatosis: A disease or a concealed warning.??
Granulomatosis is any condition characterized by the formation of multiple nodules or granulomas in the soft tissues. Differential diagnosis for orofacial region includes a wide spectrum of diseases, but most of these lesions present histopathologically as noncaseating granulomas, giving a nonspecif...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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Series: | Indian Journal of Pathology and Microbiology |
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Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2017;volume=60;issue=4;spage=556;epage=559;aulast=Bhagde |
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author | Priya Anil Bhagde Jyoti D Bhavthankar Mandakini Mandale |
author_facet | Priya Anil Bhagde Jyoti D Bhavthankar Mandakini Mandale |
author_sort | Priya Anil Bhagde |
collection | DOAJ |
description | Granulomatosis is any condition characterized by the formation of multiple nodules or granulomas in the soft tissues. Differential diagnosis for orofacial region includes a wide spectrum of diseases, but most of these lesions present histopathologically as noncaseating granulomas, giving a nonspecific depiction and leading to a diagnostic impasse. In the absence of any diagnosable entity, the disease is labelled as “orofacial granulomatosis”. A nine-year-old girl child reported with recurrent gingival enlargement and persistent macrochelia which histopathologically presented as noncaseating granulomas. The disease was progressive raising the suspicion of being oral manifestation of a systemic disorder such as Sarcoidosis or Crohn's disease. This paper throws some light on this rare entity and reports rarer features of this disease, like eye involvement and staphylococcal mucositis in the case report. |
first_indexed | 2024-04-12T23:26:44Z |
format | Article |
id | doaj.art-17f4f47f8b624ce7aa33ba3fa446c581 |
institution | Directory Open Access Journal |
issn | 0377-4929 |
language | English |
last_indexed | 2024-04-12T23:26:44Z |
publishDate | 2017-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Indian Journal of Pathology and Microbiology |
spelling | doaj.art-17f4f47f8b624ce7aa33ba3fa446c5812022-12-22T03:12:23ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292017-01-0160455655910.4103/IJPM.IJPM_401_17Orofacial granulomatosis: A disease or a concealed warning.??Priya Anil BhagdeJyoti D BhavthankarMandakini MandaleGranulomatosis is any condition characterized by the formation of multiple nodules or granulomas in the soft tissues. Differential diagnosis for orofacial region includes a wide spectrum of diseases, but most of these lesions present histopathologically as noncaseating granulomas, giving a nonspecific depiction and leading to a diagnostic impasse. In the absence of any diagnosable entity, the disease is labelled as “orofacial granulomatosis”. A nine-year-old girl child reported with recurrent gingival enlargement and persistent macrochelia which histopathologically presented as noncaseating granulomas. The disease was progressive raising the suspicion of being oral manifestation of a systemic disorder such as Sarcoidosis or Crohn's disease. This paper throws some light on this rare entity and reports rarer features of this disease, like eye involvement and staphylococcal mucositis in the case report.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2017;volume=60;issue=4;spage=556;epage=559;aulast=BhagdeCrohn's diseaseorofacial granulomatosissarcoidosis |
spellingShingle | Priya Anil Bhagde Jyoti D Bhavthankar Mandakini Mandale Orofacial granulomatosis: A disease or a concealed warning.?? Indian Journal of Pathology and Microbiology Crohn's disease orofacial granulomatosis sarcoidosis |
title | Orofacial granulomatosis: A disease or a concealed warning.?? |
title_full | Orofacial granulomatosis: A disease or a concealed warning.?? |
title_fullStr | Orofacial granulomatosis: A disease or a concealed warning.?? |
title_full_unstemmed | Orofacial granulomatosis: A disease or a concealed warning.?? |
title_short | Orofacial granulomatosis: A disease or a concealed warning.?? |
title_sort | orofacial granulomatosis a disease or a concealed warning |
topic | Crohn's disease orofacial granulomatosis sarcoidosis |
url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2017;volume=60;issue=4;spage=556;epage=559;aulast=Bhagde |
work_keys_str_mv | AT priyaanilbhagde orofacialgranulomatosisadiseaseoraconcealedwarning AT jyotidbhavthankar orofacialgranulomatosisadiseaseoraconcealedwarning AT mandakinimandale orofacialgranulomatosisadiseaseoraconcealedwarning |