Effects of Hydroxyapatite on Bone Graft Resorption in an Experimental Model of Maxillary Alveolar Arch Defects
Most commonly used treatments use autologous bone grafts to address bony defects in patients with cleft palate. Major disadvantages of autogenous bone grafts include donor site morbidity and resorption. Suggestions to overcome such problems include biomaterials that can be used alone or in combinati...
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| Format: | Article |
| Language: | English |
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GESDAV
2013-06-01
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| Series: | Archives of Clinical and Experimental Surgery |
| Subjects: | |
| Online Access: | http://www.scopemed.org/fulltextpdf.php?mno=25457 |
| _version_ | 1797923146397908992 |
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| author | Ozgur Pilanci Can Cinar Samet Vasfi Kuvat Muzaffer Altintas Zeki Guzel Ali Kilic |
| author_facet | Ozgur Pilanci Can Cinar Samet Vasfi Kuvat Muzaffer Altintas Zeki Guzel Ali Kilic |
| author_sort | Ozgur Pilanci |
| collection | DOAJ |
| description | Most commonly used treatments use autologous bone grafts to address bony defects in patients with cleft palate. Major disadvantages of autogenous bone grafts include donor site morbidity and resorption. Suggestions to overcome such problems include biomaterials that can be used alone or in combination with bone. We examined the effect of hydroxyapatite cement on bone graft resorption in a rabbit maxillary alveolar defect model. We divided 16 young adult albino New Zealand rabbits into two groups. A defect 1 cm wide was created in each rabbit's maxillary arch. In Group 1, the removed bone was disrupted, and the pieces were replaced in the defect. In the other group, the pieces were replaced after mixing (1:1) with hydroxyapatite cement. Quantitative computed tomographic evaluation of these grafts was performed in axial and coronal planes for each rabbit at 2 and 12 weeks. In axial images at 12 weeks, the group without cement showed mean bone resorption of 15%. In the cement group, a mean volumetric increase of 68% was seen. No resorption occurred when bone grafts were mixed with hydroxyapatite cement. [Arch Clin Exp Surg 2013; 2(3.000): 170-175] |
| first_indexed | 2024-04-10T14:42:13Z |
| format | Article |
| id | doaj.art-17f5159c50b541179b026039bb54a189 |
| institution | Directory Open Access Journal |
| issn | 2146-8133 |
| language | English |
| last_indexed | 2024-04-10T14:42:13Z |
| publishDate | 2013-06-01 |
| publisher | GESDAV |
| record_format | Article |
| series | Archives of Clinical and Experimental Surgery |
| spelling | doaj.art-17f5159c50b541179b026039bb54a1892023-02-15T16:08:06ZengGESDAVArchives of Clinical and Experimental Surgery2146-81332013-06-012317017510.5455/aces.2012101812313725457Effects of Hydroxyapatite on Bone Graft Resorption in an Experimental Model of Maxillary Alveolar Arch DefectsOzgur Pilanci0Can Cinar1Samet Vasfi Kuvat2Muzaffer Altintas3Zeki Guzel4Ali Kilic5istanbul University, Cerrahpasa Faculty of Medicine istanbul University, Cerrahpasa Faculty of Medicine istanbul University, Istanbul Faculty of Medicine istanbul University, Cerrahpasa Faculty of Medicine istanbul University, Cerrahpasa Faculty of Medicine istanbul University, Cerrahpasa Faculty of MedicineMost commonly used treatments use autologous bone grafts to address bony defects in patients with cleft palate. Major disadvantages of autogenous bone grafts include donor site morbidity and resorption. Suggestions to overcome such problems include biomaterials that can be used alone or in combination with bone. We examined the effect of hydroxyapatite cement on bone graft resorption in a rabbit maxillary alveolar defect model. We divided 16 young adult albino New Zealand rabbits into two groups. A defect 1 cm wide was created in each rabbit's maxillary arch. In Group 1, the removed bone was disrupted, and the pieces were replaced in the defect. In the other group, the pieces were replaced after mixing (1:1) with hydroxyapatite cement. Quantitative computed tomographic evaluation of these grafts was performed in axial and coronal planes for each rabbit at 2 and 12 weeks. In axial images at 12 weeks, the group without cement showed mean bone resorption of 15%. In the cement group, a mean volumetric increase of 68% was seen. No resorption occurred when bone grafts were mixed with hydroxyapatite cement. [Arch Clin Exp Surg 2013; 2(3.000): 170-175]http://www.scopemed.org/fulltextpdf.php?mno=25457Hydroxyapatitebone graft resorptionalveolar bone graft |
| spellingShingle | Ozgur Pilanci Can Cinar Samet Vasfi Kuvat Muzaffer Altintas Zeki Guzel Ali Kilic Effects of Hydroxyapatite on Bone Graft Resorption in an Experimental Model of Maxillary Alveolar Arch Defects Archives of Clinical and Experimental Surgery Hydroxyapatite bone graft resorption alveolar bone graft |
| title | Effects of Hydroxyapatite on Bone Graft Resorption in an Experimental Model of Maxillary Alveolar Arch Defects |
| title_full | Effects of Hydroxyapatite on Bone Graft Resorption in an Experimental Model of Maxillary Alveolar Arch Defects |
| title_fullStr | Effects of Hydroxyapatite on Bone Graft Resorption in an Experimental Model of Maxillary Alveolar Arch Defects |
| title_full_unstemmed | Effects of Hydroxyapatite on Bone Graft Resorption in an Experimental Model of Maxillary Alveolar Arch Defects |
| title_short | Effects of Hydroxyapatite on Bone Graft Resorption in an Experimental Model of Maxillary Alveolar Arch Defects |
| title_sort | effects of hydroxyapatite on bone graft resorption in an experimental model of maxillary alveolar arch defects |
| topic | Hydroxyapatite bone graft resorption alveolar bone graft |
| url | http://www.scopemed.org/fulltextpdf.php?mno=25457 |
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