Alpelisib as a new treatment option for patients with the PIK3CA mutation. The effectiveness and tolerability of therapy on the example of a clinical case
The PI3K / AKT / mTOR pathway plays a key role in the regulation of cell proliferation, growth and survival. It was found that the PIK3CA mutation, an oncogene encoding the catalytic isoform of PI3K kinase p110α, is one of the most frequent somatic mutations in breast cancer: it is found in about 20...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Remedium Group LLC
2021-06-01
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| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/6216 |