IgG4-Related Disease with Esophageal Involvement
We report the case of a 56-year-old man who presented with dysphagia and weight loss. An esophagoduodenoscopy revealed a severe esophageal stricture in the distal esophagus. After surgical resection, the final pathologic analysis revealed that the tumor was comprised of benign-appearing fibroinflamm...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2019-09-01
|
| Series: | Case Reports in Gastroenterology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/502794 |
| _version_ | 1819319625296379904 |
|---|---|
| author | Sung Wook Jang Min Ho Jeon Hyun Deok Shin |
| author_facet | Sung Wook Jang Min Ho Jeon Hyun Deok Shin |
| author_sort | Sung Wook Jang |
| collection | DOAJ |
| description | We report the case of a 56-year-old man who presented with dysphagia and weight loss. An esophagoduodenoscopy revealed a severe esophageal stricture in the distal esophagus. After surgical resection, the final pathologic analysis revealed that the tumor was comprised of benign-appearing fibroinflammatory cells with an increase and predominance of IgG4-positive plasma cells. He did not, however, have any other symptoms indicative of systemic autoimmune disease or connective tissue disorders. Histologically, abundant infiltration of IgG4-positive plasma cells and lymphocytes was observed. The patient was diagnosed with IgG4-related disease, definitive, with esophageal involvement. |
| first_indexed | 2024-12-24T11:06:39Z |
| format | Article |
| id | doaj.art-17f79fc43f6d4c4784ce6169841b691c |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-12-24T11:06:39Z |
| publishDate | 2019-09-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-17f79fc43f6d4c4784ce6169841b691c2022-12-21T16:58:36ZengKarger PublishersCase Reports in Gastroenterology1662-06312019-09-0113336937510.1159/000502794502794IgG4-Related Disease with Esophageal InvolvementSung Wook JangMin Ho JeonHyun Deok ShinWe report the case of a 56-year-old man who presented with dysphagia and weight loss. An esophagoduodenoscopy revealed a severe esophageal stricture in the distal esophagus. After surgical resection, the final pathologic analysis revealed that the tumor was comprised of benign-appearing fibroinflammatory cells with an increase and predominance of IgG4-positive plasma cells. He did not, however, have any other symptoms indicative of systemic autoimmune disease or connective tissue disorders. Histologically, abundant infiltration of IgG4-positive plasma cells and lymphocytes was observed. The patient was diagnosed with IgG4-related disease, definitive, with esophageal involvement.https://www.karger.com/Article/FullText/502794IgG4-related diseaseEsophagusAutoimmune esophagitis |
| spellingShingle | Sung Wook Jang Min Ho Jeon Hyun Deok Shin IgG4-Related Disease with Esophageal Involvement Case Reports in Gastroenterology IgG4-related disease Esophagus Autoimmune esophagitis |
| title | IgG4-Related Disease with Esophageal Involvement |
| title_full | IgG4-Related Disease with Esophageal Involvement |
| title_fullStr | IgG4-Related Disease with Esophageal Involvement |
| title_full_unstemmed | IgG4-Related Disease with Esophageal Involvement |
| title_short | IgG4-Related Disease with Esophageal Involvement |
| title_sort | igg4 related disease with esophageal involvement |
| topic | IgG4-related disease Esophagus Autoimmune esophagitis |
| url | https://www.karger.com/Article/FullText/502794 |
| work_keys_str_mv | AT sungwookjang igg4relateddiseasewithesophagealinvolvement AT minhojeon igg4relateddiseasewithesophagealinvolvement AT hyundeokshin igg4relateddiseasewithesophagealinvolvement |