Mechanism of coupling drug transport reactions located in two different membranes

Mechanism of coupling drug transport reactions located in two different membranes

Gram- negative bacteria utilize a diverse array of multidrug transporters to pump toxic compounds out of cells. Some transporters together with periplasmic membrane fusion proteins (MFPs) and outer membrane channels assemble trans-envelope complexes that expel multiple antibiotics across outer membr...

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Bibliographic Details
Main Authors:	Helen I. Zgurskaya, Jon W. Weeks, Abigail T. Ntreh, Logan M. Nickels, David eWolloscheck
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-02-01
Series:	Frontiers in Microbiology
Subjects:	Gram-Negative Bacteria antibiotic resistance drug efflux periplasmic membrane fusion proteins outer membrane factors
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00100/full

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