Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in children

Рurpose. The aim is to study the influence of primary Mycobacterium tuberculosis infection on the occurrence of bronchial obstruction syndrome in children. Materials and methods. A retrospective study of primary medical records of 60 children aged 2 to 6 years for the period from 2016 to 2018, with...

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Main Authors: A. L. Salova, O. G. Chelnokova, L. I. Mozzhukhina, T. A. Kogut
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2020-12-01
Series:Детские инфекции (Москва)
Subjects:
Online Access:https://detinf.elpub.ru/jour/article/view/545
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author A. L. Salova
O. G. Chelnokova
L. I. Mozzhukhina
T. A. Kogut
author_facet A. L. Salova
O. G. Chelnokova
L. I. Mozzhukhina
T. A. Kogut
author_sort A. L. Salova
collection DOAJ
description Рurpose. The aim is to study the influence of primary Mycobacterium tuberculosis infection on the occurrence of bronchial obstruction syndrome in children. Materials and methods. A retrospective study of primary medical records of 60 children aged 2 to 6 years for the period from 2016 to 2018, with diagnoses of acute obstructive bronchitis and acute respiratory infection. The patients were divided into 2 groups: group I — 30 children with bronchial obstruction syndrome, II group — 30 people — children with common cold without bronchial obstruction syndrome (control group). We studied the dynamics of reactions to the Mantoux test with 2 TE, contacts with tuberculosis patients, the effectiveness of Vaccinum tuberculosis (BCG-M) vaccination, allergological history, the nature of feeding and allergizing factors in everyday life. Data processing was performed using the NanoStat 1.6 program. Тhe сritical level of statistical significance was assumed to be p < 0.05. Results. It was found that primary Mycobacterium tuberculosis (MBT) infection in children under 4 years has a direct correlation with a high risk of bronchial obstruction syndrome. At the same time, bronchial obstruction syndrome occurred in the absence of local tuberculosis, which can be considered as a paraspecific reaction in the case of primary MBT infection. Сonclusions. The observed relationship between the two phenomena determines the need to examine young children with bronchial obstruction syndrome for MBT infection.
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spelling doaj.art-17fa851581184c7f9cc619828639ae0c2025-03-05T13:50:45ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072020-12-01194343710.22627/2072-8107-2020-19-4-34-37472Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in childrenA. L. Salova0O. G. Chelnokova1L. I. Mozzhukhina2T. A. Kogut3Yaroslavl state medical University of the Ministry of health of the Russian FederationYaroslavl state medical University of the Ministry of health of the Russian FederationYaroslavl state medical University of the Ministry of health of the Russian FederationYaroslavl state medical University of the Ministry of health of the Russian FederationРurpose. The aim is to study the influence of primary Mycobacterium tuberculosis infection on the occurrence of bronchial obstruction syndrome in children. Materials and methods. A retrospective study of primary medical records of 60 children aged 2 to 6 years for the period from 2016 to 2018, with diagnoses of acute obstructive bronchitis and acute respiratory infection. The patients were divided into 2 groups: group I — 30 children with bronchial obstruction syndrome, II group — 30 people — children with common cold without bronchial obstruction syndrome (control group). We studied the dynamics of reactions to the Mantoux test with 2 TE, contacts with tuberculosis patients, the effectiveness of Vaccinum tuberculosis (BCG-M) vaccination, allergological history, the nature of feeding and allergizing factors in everyday life. Data processing was performed using the NanoStat 1.6 program. Тhe сritical level of statistical significance was assumed to be p < 0.05. Results. It was found that primary Mycobacterium tuberculosis (MBT) infection in children under 4 years has a direct correlation with a high risk of bronchial obstruction syndrome. At the same time, bronchial obstruction syndrome occurred in the absence of local tuberculosis, which can be considered as a paraspecific reaction in the case of primary MBT infection. Сonclusions. The observed relationship between the two phenomena determines the need to examine young children with bronchial obstruction syndrome for MBT infection.https://detinf.elpub.ru/jour/article/view/545bronchial obstructive syndromeprimary infection with mycobacterium tuberculosis
spellingShingle A. L. Salova
O. G. Chelnokova
L. I. Mozzhukhina
T. A. Kogut
Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in children
Детские инфекции (Москва)
bronchial obstructive syndrome
primary infection with mycobacterium tuberculosis
title Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in children
title_full Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in children
title_fullStr Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in children
title_full_unstemmed Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in children
title_short Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in children
title_sort bronchial obstructive syndrome in primary infection with mycobacterium tuberculosis in children
topic bronchial obstructive syndrome
primary infection with mycobacterium tuberculosis
url https://detinf.elpub.ru/jour/article/view/545
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AT ogchelnokova bronchialobstructivesyndromeinprimaryinfectionwithmycobacteriumtuberculosisinchildren
AT limozzhukhina bronchialobstructivesyndromeinprimaryinfectionwithmycobacteriumtuberculosisinchildren
AT takogut bronchialobstructivesyndromeinprimaryinfectionwithmycobacteriumtuberculosisinchildren