The Bisindole Alkaloid Caulerpin, from Seaweeds of the Genus Caulerpa, Attenuated Colon Damage in Murine Colitis Model

The Bisindole Alkaloid Caulerpin, from Seaweeds of the Genus Caulerpa, Attenuated Colon Damage in Murine Colitis Model

Caulerpin (CLP), an alkaloid from algae of the genus Caulerpa, has shown anti-inflammatory activity. Therefore, this study aimed to analyze the effect of CLP in the murine model of peritonitis and ulcerative colitis. Firstly, the mice were submitted to peritonitis to evaluate which dose of CLP (40,...

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Bibliographic Details
Main Authors: Alessandra M. M. Lucena, Cássio R. M. Souza, Jéssica T. Jales, Paulo M. M. Guedes, George E. C. de Miranda, Adolpho M. A. de Moura, João X. Araújo-Júnior, George J. Nascimento, Kátia C. Scortecci, Barbara V. O. Santos, Janeusa T. Souto
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Marine Drugs
Subjects:
caulerpin
ulcerative colitis
anti-inflammatory activity
cytokines
tissue damage
Online Access:http://www.mdpi.com/1660-3397/16/9/318

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