A Review of Traditional Chinese Medicine, Buyang Huanwu Decoction for the Treatment of Cerebral Small Vessel Disease
Cerebral small vessel disease (CSVD) is often referred to as “collaterals disease” in traditional Chinese medicine (TCM), and commonly includes ischemic and hemorrhagic CSVD. TCM has a long history of treating CSVD and has demonstrated unique efficacy. Buyang Huanwu Decoction (BHD) is a classical TC...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2022.942188/full |
| _version_ | 1811332805292982272 |
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| author | Liying Sun Xuhui Ye Linlin Wang Junping Yu Yan Wu Minpeng Wang Lihua Dai |
| author_facet | Liying Sun Xuhui Ye Linlin Wang Junping Yu Yan Wu Minpeng Wang Lihua Dai |
| author_sort | Liying Sun |
| collection | DOAJ |
| description | Cerebral small vessel disease (CSVD) is often referred to as “collaterals disease” in traditional Chinese medicine (TCM), and commonly includes ischemic and hemorrhagic CSVD. TCM has a long history of treating CSVD and has demonstrated unique efficacy. Buyang Huanwu Decoction (BHD) is a classical TCM formula that has been used for the prevention and treatment of stroke for hundreds of years. BHD exerts its therapeutic effects on CSVD through a variety of mechanisms. In this review, the clinical and animal studies on BHD and CSVD were systematically introduced. In addition, the pharmacological mechanisms, active components, and clinical applications of BHD in the treatment of CSVD were reviewed. We believe that an in-depth understanding of BHD, its pharmacological mechanism, disease-drug interaction, and other aspects will help in laying the foundation for its development as a new therapeutic strategy for the treatment of CSVD. |
| first_indexed | 2024-04-13T16:42:28Z |
| format | Article |
| id | doaj.art-180516dc25df4ef0812fdf10c02325b8 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-04-13T16:42:28Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-180516dc25df4ef0812fdf10c02325b82022-12-22T02:39:10ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2022-06-011610.3389/fnins.2022.942188942188A Review of Traditional Chinese Medicine, Buyang Huanwu Decoction for the Treatment of Cerebral Small Vessel DiseaseLiying SunXuhui YeLinlin WangJunping YuYan WuMinpeng WangLihua DaiCerebral small vessel disease (CSVD) is often referred to as “collaterals disease” in traditional Chinese medicine (TCM), and commonly includes ischemic and hemorrhagic CSVD. TCM has a long history of treating CSVD and has demonstrated unique efficacy. Buyang Huanwu Decoction (BHD) is a classical TCM formula that has been used for the prevention and treatment of stroke for hundreds of years. BHD exerts its therapeutic effects on CSVD through a variety of mechanisms. In this review, the clinical and animal studies on BHD and CSVD were systematically introduced. In addition, the pharmacological mechanisms, active components, and clinical applications of BHD in the treatment of CSVD were reviewed. We believe that an in-depth understanding of BHD, its pharmacological mechanism, disease-drug interaction, and other aspects will help in laying the foundation for its development as a new therapeutic strategy for the treatment of CSVD.https://www.frontiersin.org/articles/10.3389/fnins.2022.942188/fullBuyang Huanwu Decoctioncerebral small vessel diseasecollaterals diseasepharmacodynamicsactive component |
| spellingShingle | Liying Sun Xuhui Ye Linlin Wang Junping Yu Yan Wu Minpeng Wang Lihua Dai A Review of Traditional Chinese Medicine, Buyang Huanwu Decoction for the Treatment of Cerebral Small Vessel Disease Frontiers in Neuroscience Buyang Huanwu Decoction cerebral small vessel disease collaterals disease pharmacodynamics active component |
| title | A Review of Traditional Chinese Medicine, Buyang Huanwu Decoction for the Treatment of Cerebral Small Vessel Disease |
| title_full | A Review of Traditional Chinese Medicine, Buyang Huanwu Decoction for the Treatment of Cerebral Small Vessel Disease |
| title_fullStr | A Review of Traditional Chinese Medicine, Buyang Huanwu Decoction for the Treatment of Cerebral Small Vessel Disease |
| title_full_unstemmed | A Review of Traditional Chinese Medicine, Buyang Huanwu Decoction for the Treatment of Cerebral Small Vessel Disease |
| title_short | A Review of Traditional Chinese Medicine, Buyang Huanwu Decoction for the Treatment of Cerebral Small Vessel Disease |
| title_sort | review of traditional chinese medicine buyang huanwu decoction for the treatment of cerebral small vessel disease |
| topic | Buyang Huanwu Decoction cerebral small vessel disease collaterals disease pharmacodynamics active component |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2022.942188/full |
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