Contact Lenses Loaded with Melatonin Analogs: A Promising Therapeutic Tool against Dry Eye Disease

Contact Lenses Loaded with Melatonin Analogs: A Promising Therapeutic Tool against Dry Eye Disease

Melatonin analogs topically administered evoke a potent tear secretagogue effect in rabbits. This route of drug administration requires high drug concentration and frequent dosing due to its reduced ocular surface retention. Therefore, contact lenses (CLs) have emerged as an alternative drug-deliver...

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Bibliographic Details
Main Authors: Francisco Javier Navarro-Gil, Fernando Huete-Toral, Carmen Olalla Domínguez-Godínez, Gonzalo Carracedo, Almudena Crooke
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Journal of Clinical Medicine
Subjects:
drug delivery
contact lenses
5-methoxycarbonylamino-N-cetyltryptamine
agomelatine
dry eye
Online Access:https://www.mdpi.com/2077-0383/11/12/3483

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