Angiolymphoid hyperplasia with eosinophilia of oral mucosa in a child treated with imiquimod

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare and idiopathic disorder of blood vessels which is common in head and neck area of middle-aged women. We report a case of angiolymphoid hyperplasia of lower lip in a 7-year-old child, confirmed by histopathological findings of hyperplastic...

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Main Authors: Anandan Venkatesan, Rashmi Singh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Indian Journal of Paediatric Dermatology
Subjects:
Online Access:http://www.ijpd.in/article.asp?issn=2319-7250;year=2016;volume=17;issue=3;spage=196;epage=198;aulast=Venkatesan
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author Anandan Venkatesan
Rashmi Singh
author_facet Anandan Venkatesan
Rashmi Singh
author_sort Anandan Venkatesan
collection DOAJ
description Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare and idiopathic disorder of blood vessels which is common in head and neck area of middle-aged women. We report a case of angiolymphoid hyperplasia of lower lip in a 7-year-old child, confirmed by histopathological findings of hyperplastic lymphoid follicles, eosinophilia, and proliferation of vessels and positive staining with CD3 and CD20 in immunohistochemistry. Lesion was treated with imiquimod for 16 weeks following which it resolved completely. We present this case for the rarity of the case in this age group on an atypical rare site. To the best of our knowledge, this is the first reported case of ALHE on oral mucosa of a male child.
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spelling doaj.art-180aa72532384102aac59fb0eaf511d72022-12-21T18:57:17ZengWolters Kluwer Medknow PublicationsIndian Journal of Paediatric Dermatology2319-72502016-01-0117319619810.4103/2319-7250.179640Angiolymphoid hyperplasia with eosinophilia of oral mucosa in a child treated with imiquimodAnandan VenkatesanRashmi SinghAngiolymphoid hyperplasia with eosinophilia (ALHE) is a rare and idiopathic disorder of blood vessels which is common in head and neck area of middle-aged women. We report a case of angiolymphoid hyperplasia of lower lip in a 7-year-old child, confirmed by histopathological findings of hyperplastic lymphoid follicles, eosinophilia, and proliferation of vessels and positive staining with CD3 and CD20 in immunohistochemistry. Lesion was treated with imiquimod for 16 weeks following which it resolved completely. We present this case for the rarity of the case in this age group on an atypical rare site. To the best of our knowledge, this is the first reported case of ALHE on oral mucosa of a male child.http://www.ijpd.in/article.asp?issn=2319-7250;year=2016;volume=17;issue=3;spage=196;epage=198;aulast=VenkatesanAngiolymphoid hyperplasiamucous membranenodule
spellingShingle Anandan Venkatesan
Rashmi Singh
Angiolymphoid hyperplasia with eosinophilia of oral mucosa in a child treated with imiquimod
Indian Journal of Paediatric Dermatology
Angiolymphoid hyperplasia
mucous membrane
nodule
title Angiolymphoid hyperplasia with eosinophilia of oral mucosa in a child treated with imiquimod
title_full Angiolymphoid hyperplasia with eosinophilia of oral mucosa in a child treated with imiquimod
title_fullStr Angiolymphoid hyperplasia with eosinophilia of oral mucosa in a child treated with imiquimod
title_full_unstemmed Angiolymphoid hyperplasia with eosinophilia of oral mucosa in a child treated with imiquimod
title_short Angiolymphoid hyperplasia with eosinophilia of oral mucosa in a child treated with imiquimod
title_sort angiolymphoid hyperplasia with eosinophilia of oral mucosa in a child treated with imiquimod
topic Angiolymphoid hyperplasia
mucous membrane
nodule
url http://www.ijpd.in/article.asp?issn=2319-7250;year=2016;volume=17;issue=3;spage=196;epage=198;aulast=Venkatesan
work_keys_str_mv AT anandanvenkatesan angiolymphoidhyperplasiawitheosinophiliaoforalmucosainachildtreatedwithimiquimod
AT rashmisingh angiolymphoidhyperplasiawitheosinophiliaoforalmucosainachildtreatedwithimiquimod