Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review

Medicinal and aromatic plants and their refined natural products have gained global attraction for their therapeutic potential against many human diseases. Nigella sativa is a medicinally important plant, commonly known as Black cumin or Black seed is a dicotyledon plant of the Ranunculaceae family....

Full description

Bibliographic Details
Main Authors: Abeer Kazmi, Mubarak Ali Khan, Huma Ali
Format: Article
Language:English
Published: International Journal of Secondary Metabolite 2019-07-01
Series:International Journal of Secondary Metabolite
Subjects:
Online Access:https://dergipark.org.tr/tr/pub/ijsm/issue/44217/575075?publisher=ijate
_version_ 1797910489303351296
author Abeer Kazmi
Mubarak Ali Khan
Huma Ali
author_facet Abeer Kazmi
Mubarak Ali Khan
Huma Ali
author_sort Abeer Kazmi
collection DOAJ
description Medicinal and aromatic plants and their refined natural products have gained global attraction for their therapeutic potential against many human diseases. Nigella sativa is a medicinally important plant, commonly known as Black cumin or Black seed is a dicotyledon plant of the Ranunculaceae family. It is in common use for a longer time in history as preservative and spice and has also been extensively utilized by different communities around the globe. Black cumin has been an eminent component of traditional medicine systems like Unani and Tibb, Ayurveda and Siddha. Its biological activities include antidiarrheal, analgesic, antibacterial, liver tonic, diurectic, digestive agent and to treat several skin disorders. Furthermore, the therapeutic properties also include antidiabetic, anticancer, antihypertensive, anti-inflammatory, hepatoprotective, spasmolytic and bronchodialator. This is all because of its miraculous healing power that it has been ranked as top ranked, among evidence based herbal medicines. The literature supports that the pharmacological activities of Nigella sativa are mainly because of the essential oil and its constituents particularly thymoquinone. The current review is an attempt to present a detailed literature survey regarding chemical composition, phytochemistry, therapeutic potential and biotechnological approaches to enhance the medicinal potential of this valuable plant.
first_indexed 2024-04-10T11:25:11Z
format Article
id doaj.art-1810403a54f546b981df89f3e90845b6
institution Directory Open Access Journal
issn 2148-6905
language English
last_indexed 2024-04-10T11:25:11Z
publishDate 2019-07-01
publisher International Journal of Secondary Metabolite
record_format Article
series International Journal of Secondary Metabolite
spelling doaj.art-1810403a54f546b981df89f3e90845b62023-02-15T16:18:24ZengInternational Journal of Secondary MetaboliteInternational Journal of Secondary Metabolite2148-69052019-07-016217219510.21448/ijsm.575075618Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date reviewAbeer KazmiMubarak Ali KhanHuma AliMedicinal and aromatic plants and their refined natural products have gained global attraction for their therapeutic potential against many human diseases. Nigella sativa is a medicinally important plant, commonly known as Black cumin or Black seed is a dicotyledon plant of the Ranunculaceae family. It is in common use for a longer time in history as preservative and spice and has also been extensively utilized by different communities around the globe. Black cumin has been an eminent component of traditional medicine systems like Unani and Tibb, Ayurveda and Siddha. Its biological activities include antidiarrheal, analgesic, antibacterial, liver tonic, diurectic, digestive agent and to treat several skin disorders. Furthermore, the therapeutic properties also include antidiabetic, anticancer, antihypertensive, anti-inflammatory, hepatoprotective, spasmolytic and bronchodialator. This is all because of its miraculous healing power that it has been ranked as top ranked, among evidence based herbal medicines. The literature supports that the pharmacological activities of Nigella sativa are mainly because of the essential oil and its constituents particularly thymoquinone. The current review is an attempt to present a detailed literature survey regarding chemical composition, phytochemistry, therapeutic potential and biotechnological approaches to enhance the medicinal potential of this valuable plant.https://dergipark.org.tr/tr/pub/ijsm/issue/44217/575075?publisher=ijatechemical compositionmedicinal significancenigella sativablack cuminphytochemistrytherapeutic potentialbiotechnological approaches
spellingShingle Abeer Kazmi
Mubarak Ali Khan
Huma Ali
Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review
International Journal of Secondary Metabolite
chemical composition
medicinal significance
nigella sativa
black cumin
phytochemistry
therapeutic potential
biotechnological approaches
title Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review
title_full Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review
title_fullStr Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review
title_full_unstemmed Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review
title_short Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review
title_sort biotechnological approaches for production of bioactive secondary metabolites in nigella sativa an up to date review
topic chemical composition
medicinal significance
nigella sativa
black cumin
phytochemistry
therapeutic potential
biotechnological approaches
url https://dergipark.org.tr/tr/pub/ijsm/issue/44217/575075?publisher=ijate
work_keys_str_mv AT abeerkazmi biotechnologicalapproachesforproductionofbioactivesecondarymetabolitesinnigellasativaanuptodatereview
AT mubarakalikhan biotechnologicalapproachesforproductionofbioactivesecondarymetabolitesinnigellasativaanuptodatereview
AT humaali biotechnologicalapproachesforproductionofbioactivesecondarymetabolitesinnigellasativaanuptodatereview