Materials and manufacturing perspectives in engineering heart valves: a review
Valvular heart diseases (VHD) are a major health burden, affecting millions of people worldwide. The treatments for such diseases rely on medicine, valve repair, and artificial heart valves including mechanical and bioprosthetic valves. Yet, there are countless reports on possible alternatives notin...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-01-01
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| Series: | Materials Today Bio |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S259000641930064X |
| _version_ | 1819163735794647040 |
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| author | F. Oveissi S. Naficy A. Lee D.S. Winlaw F. Dehghani |
| author_facet | F. Oveissi S. Naficy A. Lee D.S. Winlaw F. Dehghani |
| author_sort | F. Oveissi |
| collection | DOAJ |
| description | Valvular heart diseases (VHD) are a major health burden, affecting millions of people worldwide. The treatments for such diseases rely on medicine, valve repair, and artificial heart valves including mechanical and bioprosthetic valves. Yet, there are countless reports on possible alternatives noting long-term stability and biocompatibility issues and highlighting the need for fabrication of more durable and effective replacements. This review discusses the current and potential materials that can be used for developing such valves along with existing and developing fabrication methods. With this perspective, we quantitatively compare mechanical properties of various materials that are currently used or proposed for heart valves along with their fabrication processes to identify challenges we face in creating new materials and manufacturing techniques to better mimick the performance of native heart valves. Keywords: Biofabrication, Biomaterials, Electrospinning, Valvular heart diseases, 3D printing |
| first_indexed | 2024-12-22T17:48:52Z |
| format | Article |
| id | doaj.art-1812a73802eb42f5b158c7eb96fb02c0 |
| institution | Directory Open Access Journal |
| issn | 2590-0064 |
| language | English |
| last_indexed | 2024-12-22T17:48:52Z |
| publishDate | 2020-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj.art-1812a73802eb42f5b158c7eb96fb02c02022-12-21T18:18:13ZengElsevierMaterials Today Bio2590-00642020-01-015Materials and manufacturing perspectives in engineering heart valves: a reviewF. Oveissi0S. Naficy1A. Lee2D.S. Winlaw3F. Dehghani4School of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, New South Wales, 2006, AustraliaSchool of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, New South Wales, 2006, Australia; Corresponding author.School of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, New South Wales, 2006, Australia; Discipline of Child and Adolescent Health, Sydney Medical School, Faculty of Health and Medicine, The University of Sydney, New South Wales, 2006, Australia; Heart Centre for Children, The Children's Hospital at Westmead, New South Wales, 2145, AustraliaDiscipline of Child and Adolescent Health, Sydney Medical School, Faculty of Health and Medicine, The University of Sydney, New South Wales, 2006, Australia; Heart Centre for Children, The Children's Hospital at Westmead, New South Wales, 2145, AustraliaSchool of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, New South Wales, 2006, Australia; Corresponding author.Valvular heart diseases (VHD) are a major health burden, affecting millions of people worldwide. The treatments for such diseases rely on medicine, valve repair, and artificial heart valves including mechanical and bioprosthetic valves. Yet, there are countless reports on possible alternatives noting long-term stability and biocompatibility issues and highlighting the need for fabrication of more durable and effective replacements. This review discusses the current and potential materials that can be used for developing such valves along with existing and developing fabrication methods. With this perspective, we quantitatively compare mechanical properties of various materials that are currently used or proposed for heart valves along with their fabrication processes to identify challenges we face in creating new materials and manufacturing techniques to better mimick the performance of native heart valves. Keywords: Biofabrication, Biomaterials, Electrospinning, Valvular heart diseases, 3D printinghttp://www.sciencedirect.com/science/article/pii/S259000641930064X |
| spellingShingle | F. Oveissi S. Naficy A. Lee D.S. Winlaw F. Dehghani Materials and manufacturing perspectives in engineering heart valves: a review Materials Today Bio |
| title | Materials and manufacturing perspectives in engineering heart valves: a review |
| title_full | Materials and manufacturing perspectives in engineering heart valves: a review |
| title_fullStr | Materials and manufacturing perspectives in engineering heart valves: a review |
| title_full_unstemmed | Materials and manufacturing perspectives in engineering heart valves: a review |
| title_short | Materials and manufacturing perspectives in engineering heart valves: a review |
| title_sort | materials and manufacturing perspectives in engineering heart valves a review |
| url | http://www.sciencedirect.com/science/article/pii/S259000641930064X |
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