An Overview of Polymeric Nanoplatforms to Deliver Veterinary Antimicrobials
There is an urgent need to find new solutions for the global dilemma of increasing antibiotic resistance in humans and animals. Modifying the performance of existing antibiotics using the nanocarrier drug delivery system (DDS) is a good option considering economic costs, labor costs, and time invest...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/14/4/341 |
| _version_ | 1797297314779365376 |
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| author | Yaxin Zhou Lihua Guo Guonian Dai Bing Li Yubin Bai Weiwei Wang Shulin Chen Jiyu Zhang |
| author_facet | Yaxin Zhou Lihua Guo Guonian Dai Bing Li Yubin Bai Weiwei Wang Shulin Chen Jiyu Zhang |
| author_sort | Yaxin Zhou |
| collection | DOAJ |
| description | There is an urgent need to find new solutions for the global dilemma of increasing antibiotic resistance in humans and animals. Modifying the performance of existing antibiotics using the nanocarrier drug delivery system (DDS) is a good option considering economic costs, labor costs, and time investment compared to the development of new antibiotics. Numerous studies on nanomedicine carriers that can be used for humans are available in the literature, but relatively few studies have been reported specifically for veterinary pharmaceutical products. Polymer-based nano-DDS are becoming a research hotspot in the pharmaceutical industry owing to their advantages, such as stability and modifiability. This review presents current research progress on polymer-based nanodelivery systems for veterinary antimicrobial drugs, focusing on the role of polymeric materials in enhancing drug performance. The use of polymer-based nanoformulations improves treatment compliance in livestock and companion animals, thereby reducing the workload of managers. Although promising advances have been made, many obstacles remain to be addressed before nanoformulations can be used in a clinical setting. Some crucial issues currently facing this field, including toxicity, quality control, and mass production, are discussed in this review. With the continuous optimization of nanotechnology, polymer-based DDS has shown its potential in reducing antibiotic resistance to veterinary medicines. |
| first_indexed | 2024-03-07T22:19:00Z |
| format | Article |
| id | doaj.art-18165f5388ae47b998d0ed4196015539 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-07T22:19:00Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-18165f5388ae47b998d0ed41960155392024-02-23T15:29:23ZengMDPI AGNanomaterials2079-49912024-02-0114434110.3390/nano14040341An Overview of Polymeric Nanoplatforms to Deliver Veterinary AntimicrobialsYaxin Zhou0Lihua Guo1Guonian Dai2Bing Li3Yubin Bai4Weiwei Wang5Shulin Chen6Jiyu Zhang7Key Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, ChinaShenniu Pharmaceutical Co., Ltd., Dezhou 253034, ChinaKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, ChinaKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, ChinaKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, ChinaKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, ChinaCollege of Veterinary Medicine, Northwest A & F University, Yangling 712100, ChinaKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, ChinaThere is an urgent need to find new solutions for the global dilemma of increasing antibiotic resistance in humans and animals. Modifying the performance of existing antibiotics using the nanocarrier drug delivery system (DDS) is a good option considering economic costs, labor costs, and time investment compared to the development of new antibiotics. Numerous studies on nanomedicine carriers that can be used for humans are available in the literature, but relatively few studies have been reported specifically for veterinary pharmaceutical products. Polymer-based nano-DDS are becoming a research hotspot in the pharmaceutical industry owing to their advantages, such as stability and modifiability. This review presents current research progress on polymer-based nanodelivery systems for veterinary antimicrobial drugs, focusing on the role of polymeric materials in enhancing drug performance. The use of polymer-based nanoformulations improves treatment compliance in livestock and companion animals, thereby reducing the workload of managers. Although promising advances have been made, many obstacles remain to be addressed before nanoformulations can be used in a clinical setting. Some crucial issues currently facing this field, including toxicity, quality control, and mass production, are discussed in this review. With the continuous optimization of nanotechnology, polymer-based DDS has shown its potential in reducing antibiotic resistance to veterinary medicines.https://www.mdpi.com/2079-4991/14/4/341polymeric nanoparticlesantibiotic deliverynatural polymerssynthetic polymersveterinary drugs |
| spellingShingle | Yaxin Zhou Lihua Guo Guonian Dai Bing Li Yubin Bai Weiwei Wang Shulin Chen Jiyu Zhang An Overview of Polymeric Nanoplatforms to Deliver Veterinary Antimicrobials Nanomaterials polymeric nanoparticles antibiotic delivery natural polymers synthetic polymers veterinary drugs |
| title | An Overview of Polymeric Nanoplatforms to Deliver Veterinary Antimicrobials |
| title_full | An Overview of Polymeric Nanoplatforms to Deliver Veterinary Antimicrobials |
| title_fullStr | An Overview of Polymeric Nanoplatforms to Deliver Veterinary Antimicrobials |
| title_full_unstemmed | An Overview of Polymeric Nanoplatforms to Deliver Veterinary Antimicrobials |
| title_short | An Overview of Polymeric Nanoplatforms to Deliver Veterinary Antimicrobials |
| title_sort | overview of polymeric nanoplatforms to deliver veterinary antimicrobials |
| topic | polymeric nanoparticles antibiotic delivery natural polymers synthetic polymers veterinary drugs |
| url | https://www.mdpi.com/2079-4991/14/4/341 |
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