Abrupt bilateral blindness as a rare post-acute demyelinating consequence of COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could prompt various neurological complications. Abrupt visual disturbance was reported as a rare severe manifestation of post-coronavirus disease 2019 (COVID-19). Autoimmune conditions were assumed to have an undeniable role in creation o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | eNeurologicalSci |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S240565022200020X |
| _version_ | 1817999639831379968 |
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| author | Ali Motahharynia Saba Naghavi Vahid Shaygannejad Iman Adibi |
| author_facet | Ali Motahharynia Saba Naghavi Vahid Shaygannejad Iman Adibi |
| author_sort | Ali Motahharynia |
| collection | DOAJ |
| description | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could prompt various neurological complications. Abrupt visual disturbance was reported as a rare severe manifestation of post-coronavirus disease 2019 (COVID-19). Autoimmune conditions were assumed to have an undeniable role in creation of such circumstances. This report presents a 69-year-old woman with sudden bilateral blindness three weeks after recovering from a SARS-CoV-2 infection. Demyelination due to COVID-19-related autoimmune disorder of the central nervous system (CRAD-C) was considered to be the etiology of her bilateral blindness. Due to her progressive demyelination, immunosuppressive treatments were administered, which resulted in stabilizing post-COVID-19 demyelinating lesions. Accordingly, in the case of COVID-19-related neurological deficits, especially the acute and progressive symptoms, there should be great consideration of autoimmune response to prevent serious complications; hence early diagnosis, treatment, and long-term assessment of patients are necessitated. |
| first_indexed | 2024-04-14T03:11:20Z |
| format | Article |
| id | doaj.art-1819a787d3524fb394a5c184491cf2fb |
| institution | Directory Open Access Journal |
| issn | 2405-6502 |
| language | English |
| last_indexed | 2024-04-14T03:11:20Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | eNeurologicalSci |
| spelling | doaj.art-1819a787d3524fb394a5c184491cf2fb2022-12-22T02:15:35ZengElseviereNeurologicalSci2405-65022022-09-0128100411Abrupt bilateral blindness as a rare post-acute demyelinating consequence of COVID-19Ali Motahharynia0Saba Naghavi1Vahid Shaygannejad2Iman Adibi3Center for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan 81839 83434, Iran; Isfahan Neuroscience Research Center, Kashani Hospital, Isfahan University of Medical Sciences, Isfahan 81839 83434, IranCenter for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan 81839 83434, Iran; Isfahan Neuroscience Research Center, Kashani Hospital, Isfahan University of Medical Sciences, Isfahan 81839 83434, Iran; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746 75731, IranCenter for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan 81839 83434, Iran; Isfahan Neuroscience Research Center, Kashani Hospital, Isfahan University of Medical Sciences, Isfahan 81839 83434, Iran; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746 75731, IranCenter for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan 81839 83434, Iran; Isfahan Neuroscience Research Center, Kashani Hospital, Isfahan University of Medical Sciences, Isfahan 81839 83434, Iran; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746 75731, Iran; Corresponding author at: Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746 75731, Iran.Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could prompt various neurological complications. Abrupt visual disturbance was reported as a rare severe manifestation of post-coronavirus disease 2019 (COVID-19). Autoimmune conditions were assumed to have an undeniable role in creation of such circumstances. This report presents a 69-year-old woman with sudden bilateral blindness three weeks after recovering from a SARS-CoV-2 infection. Demyelination due to COVID-19-related autoimmune disorder of the central nervous system (CRAD-C) was considered to be the etiology of her bilateral blindness. Due to her progressive demyelination, immunosuppressive treatments were administered, which resulted in stabilizing post-COVID-19 demyelinating lesions. Accordingly, in the case of COVID-19-related neurological deficits, especially the acute and progressive symptoms, there should be great consideration of autoimmune response to prevent serious complications; hence early diagnosis, treatment, and long-term assessment of patients are necessitated.http://www.sciencedirect.com/science/article/pii/S240565022200020XAutoimmunityBlindnessCOVID-19DemyelinationPost-COVID-19 syndrome |
| spellingShingle | Ali Motahharynia Saba Naghavi Vahid Shaygannejad Iman Adibi Abrupt bilateral blindness as a rare post-acute demyelinating consequence of COVID-19 eNeurologicalSci Autoimmunity Blindness COVID-19 Demyelination Post-COVID-19 syndrome |
| title | Abrupt bilateral blindness as a rare post-acute demyelinating consequence of COVID-19 |
| title_full | Abrupt bilateral blindness as a rare post-acute demyelinating consequence of COVID-19 |
| title_fullStr | Abrupt bilateral blindness as a rare post-acute demyelinating consequence of COVID-19 |
| title_full_unstemmed | Abrupt bilateral blindness as a rare post-acute demyelinating consequence of COVID-19 |
| title_short | Abrupt bilateral blindness as a rare post-acute demyelinating consequence of COVID-19 |
| title_sort | abrupt bilateral blindness as a rare post acute demyelinating consequence of covid 19 |
| topic | Autoimmunity Blindness COVID-19 Demyelination Post-COVID-19 syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S240565022200020X |
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