Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications

We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The targeted applications of these kind of materials concern the post-operative prophylaxis. The in vitro...

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Bibliographic Details
Main Authors: Daniel-Cristian Ioan, Ileana Rău, Mădălina Georgiana Albu Kaya, Nicoleta Radu, Marinela Bostan, Roxana Gabriela Zgârian, Graţiela Teodora Tihan, Cristina-Elena Dinu-Pîrvu, Alina Lupuliasa, Mihaela Violeta Ghica
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/9/1915
Description
Summary:We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The targeted applications of these kind of materials concern the post-operative prophylaxis. The in vitro tests (antimicrobial, cytotoxic, drug release) showed that sponges with a concentration of 0.75 g of ciprofloxacin per gram of collagen could be beneficial for the desired applications.
ISSN:2073-4360