Engineered Phage Endolysin Eliminates <i>Gardnerella</i> Biofilm without Damaging Beneficial Bacteria in Bacterial Vaginosis Ex Vivo
Bacterial vaginosis is characterized by an imbalance of the vaginal microbiome and a characteristic biofilm formed on the vaginal epithelium, which is initiated and dominated by <i>Gardnerella</i> bacteria, and is frequently refractory to antibiotic treatment. We investigated endolysins...
Main Authors: | Christine Landlinger, Lenka Tisakova, Vera Oberbauer, Timo Schwebs, Abbas Muhammad, Agnieszka Latka, Leen Van Simaey, Mario Vaneechoutte, Alexander Guschin, Gregory Resch, Sonja Swidsinski, Alexander Swidsinski, Lorenzo Corsini |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
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Series: | Pathogens |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-0817/10/1/54 |
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