Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia

Objective: Both a 1- to 4-week continuous or intermittent stay and moderate exercise in hypoxia versus normoxia can lead to weight loss. We examined the reproducibility and durability of added hypoxic exposure in a feasible health program of several months. Methods: 32 obese persons, randomly assign...

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Main Authors: Hannes Gatterer, Sven Haacke, Martin Burtscher, Martin Faulhaber, Andreas Melmer, Christoph Ebenbichler, Kingman P. Strohl, Josef Högel, Nikolaus C. Netzer
Format: Article
Language:English
Published: Karger Publishers 2015-05-01
Series:Obesity Facts
Subjects:
Online Access:http://www.karger.com/Article/FullText/431157
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author Hannes Gatterer
Sven Haacke
Martin Burtscher
Martin Faulhaber
Andreas Melmer
Christoph Ebenbichler
Kingman P. Strohl
Josef Högel
Nikolaus C. Netzer
author_facet Hannes Gatterer
Sven Haacke
Martin Burtscher
Martin Faulhaber
Andreas Melmer
Christoph Ebenbichler
Kingman P. Strohl
Josef Högel
Nikolaus C. Netzer
author_sort Hannes Gatterer
collection DOAJ
description Objective: Both a 1- to 4-week continuous or intermittent stay and moderate exercise in hypoxia versus normoxia can lead to weight loss. We examined the reproducibility and durability of added hypoxic exposure in a feasible health program of several months. Methods: 32 obese persons, randomly assigned to either a hypoxia (age 50.3 ± 10.3 years, BMI 37.9 ± 8.1 kg/m²) or a normoxia (age 52.4 ± 7.9 years, BMI 36.3 ± 4.0 kg/m²) group, completed 52 exercise sessions within 8 months. Participants exercised for 90 min (65-70% HRpeak) either at a simulated altitude of 3,500 m or in normoxia, and rested for further 90 min at 4,500 m or normoxia. Before, after 5 weeks, after 3 months, and after the intervention, body composition and exercise capacity were determined. Risk markers (e.g., blood pressure, cholesterol) were measured before, after 3 months, and after the intervention period. Results: Body weight, BMI, waist and hip circumference, Ppeak and BPsys improved over time (p Conclusion: Long-term, moderate intensity exercise and rest in hypoxia does not lead to higher reductions in body weight than normoxia alone. Therefore, for weight loss and metabolic markers hypoxic exposure does not add effects at least when stimuli (i.e., hypoxia dose, exercise intensity/duration) are unaltered throughout the intervention.
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spelling doaj.art-181eb6f9092e4e2b8fef71edb3b933782022-12-22T00:41:25ZengKarger PublishersObesity Facts1662-40251662-40332015-05-018320020910.1159/000431157431157Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham HypoxiaHannes GattererSven HaackeMartin BurtscherMartin FaulhaberAndreas MelmerChristoph EbenbichlerKingman P. StrohlJosef HögelNikolaus C. NetzerObjective: Both a 1- to 4-week continuous or intermittent stay and moderate exercise in hypoxia versus normoxia can lead to weight loss. We examined the reproducibility and durability of added hypoxic exposure in a feasible health program of several months. Methods: 32 obese persons, randomly assigned to either a hypoxia (age 50.3 ± 10.3 years, BMI 37.9 ± 8.1 kg/m²) or a normoxia (age 52.4 ± 7.9 years, BMI 36.3 ± 4.0 kg/m²) group, completed 52 exercise sessions within 8 months. Participants exercised for 90 min (65-70% HRpeak) either at a simulated altitude of 3,500 m or in normoxia, and rested for further 90 min at 4,500 m or normoxia. Before, after 5 weeks, after 3 months, and after the intervention, body composition and exercise capacity were determined. Risk markers (e.g., blood pressure, cholesterol) were measured before, after 3 months, and after the intervention period. Results: Body weight, BMI, waist and hip circumference, Ppeak and BPsys improved over time (p Conclusion: Long-term, moderate intensity exercise and rest in hypoxia does not lead to higher reductions in body weight than normoxia alone. Therefore, for weight loss and metabolic markers hypoxic exposure does not add effects at least when stimuli (i.e., hypoxia dose, exercise intensity/duration) are unaltered throughout the intervention.http://www.karger.com/Article/FullText/431157HypoxiaWeight lossPhysical exerciseObeseOverweight
spellingShingle Hannes Gatterer
Sven Haacke
Martin Burtscher
Martin Faulhaber
Andreas Melmer
Christoph Ebenbichler
Kingman P. Strohl
Josef Högel
Nikolaus C. Netzer
Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia
Obesity Facts
Hypoxia
Weight loss
Physical exercise
Obese
Overweight
title Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia
title_full Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia
title_fullStr Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia
title_full_unstemmed Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia
title_short Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia
title_sort normobaric intermittent hypoxia over 8 months does not reduce body weight and metabolic risk factors a randomized single blind placebo controlled study in normobaric hypoxia and normobaric sham hypoxia
topic Hypoxia
Weight loss
Physical exercise
Obese
Overweight
url http://www.karger.com/Article/FullText/431157
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