Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia
Objective: Both a 1- to 4-week continuous or intermittent stay and moderate exercise in hypoxia versus normoxia can lead to weight loss. We examined the reproducibility and durability of added hypoxic exposure in a feasible health program of several months. Methods: 32 obese persons, randomly assign...
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Karger Publishers
2015-05-01
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Series: | Obesity Facts |
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Online Access: | http://www.karger.com/Article/FullText/431157 |
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author | Hannes Gatterer Sven Haacke Martin Burtscher Martin Faulhaber Andreas Melmer Christoph Ebenbichler Kingman P. Strohl Josef Högel Nikolaus C. Netzer |
author_facet | Hannes Gatterer Sven Haacke Martin Burtscher Martin Faulhaber Andreas Melmer Christoph Ebenbichler Kingman P. Strohl Josef Högel Nikolaus C. Netzer |
author_sort | Hannes Gatterer |
collection | DOAJ |
description | Objective: Both a 1- to 4-week continuous or intermittent stay and moderate exercise in hypoxia versus normoxia can lead to weight loss. We examined the reproducibility and durability of added hypoxic exposure in a feasible health program of several months. Methods: 32 obese persons, randomly assigned to either a hypoxia (age 50.3 ± 10.3 years, BMI 37.9 ± 8.1 kg/m²) or a normoxia (age 52.4 ± 7.9 years, BMI 36.3 ± 4.0 kg/m²) group, completed 52 exercise sessions within 8 months. Participants exercised for 90 min (65-70% HRpeak) either at a simulated altitude of 3,500 m or in normoxia, and rested for further 90 min at 4,500 m or normoxia. Before, after 5 weeks, after 3 months, and after the intervention, body composition and exercise capacity were determined. Risk markers (e.g., blood pressure, cholesterol) were measured before, after 3 months, and after the intervention period. Results: Body weight, BMI, waist and hip circumference, Ppeak and BPsys improved over time (p Conclusion: Long-term, moderate intensity exercise and rest in hypoxia does not lead to higher reductions in body weight than normoxia alone. Therefore, for weight loss and metabolic markers hypoxic exposure does not add effects at least when stimuli (i.e., hypoxia dose, exercise intensity/duration) are unaltered throughout the intervention. |
first_indexed | 2024-12-12T02:31:02Z |
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id | doaj.art-181eb6f9092e4e2b8fef71edb3b93378 |
institution | Directory Open Access Journal |
issn | 1662-4025 1662-4033 |
language | English |
last_indexed | 2024-12-12T02:31:02Z |
publishDate | 2015-05-01 |
publisher | Karger Publishers |
record_format | Article |
series | Obesity Facts |
spelling | doaj.art-181eb6f9092e4e2b8fef71edb3b933782022-12-22T00:41:25ZengKarger PublishersObesity Facts1662-40251662-40332015-05-018320020910.1159/000431157431157Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham HypoxiaHannes GattererSven HaackeMartin BurtscherMartin FaulhaberAndreas MelmerChristoph EbenbichlerKingman P. StrohlJosef HögelNikolaus C. NetzerObjective: Both a 1- to 4-week continuous or intermittent stay and moderate exercise in hypoxia versus normoxia can lead to weight loss. We examined the reproducibility and durability of added hypoxic exposure in a feasible health program of several months. Methods: 32 obese persons, randomly assigned to either a hypoxia (age 50.3 ± 10.3 years, BMI 37.9 ± 8.1 kg/m²) or a normoxia (age 52.4 ± 7.9 years, BMI 36.3 ± 4.0 kg/m²) group, completed 52 exercise sessions within 8 months. Participants exercised for 90 min (65-70% HRpeak) either at a simulated altitude of 3,500 m or in normoxia, and rested for further 90 min at 4,500 m or normoxia. Before, after 5 weeks, after 3 months, and after the intervention, body composition and exercise capacity were determined. Risk markers (e.g., blood pressure, cholesterol) were measured before, after 3 months, and after the intervention period. Results: Body weight, BMI, waist and hip circumference, Ppeak and BPsys improved over time (p Conclusion: Long-term, moderate intensity exercise and rest in hypoxia does not lead to higher reductions in body weight than normoxia alone. Therefore, for weight loss and metabolic markers hypoxic exposure does not add effects at least when stimuli (i.e., hypoxia dose, exercise intensity/duration) are unaltered throughout the intervention.http://www.karger.com/Article/FullText/431157HypoxiaWeight lossPhysical exerciseObeseOverweight |
spellingShingle | Hannes Gatterer Sven Haacke Martin Burtscher Martin Faulhaber Andreas Melmer Christoph Ebenbichler Kingman P. Strohl Josef Högel Nikolaus C. Netzer Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia Obesity Facts Hypoxia Weight loss Physical exercise Obese Overweight |
title | Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia |
title_full | Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia |
title_fullStr | Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia |
title_full_unstemmed | Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia |
title_short | Normobaric Intermittent Hypoxia over 8 Months Does Not Reduce Body Weight and Metabolic Risk Factors - a Randomized, Single Blind, Placebo-Controlled Study in Normobaric Hypoxia and Normobaric Sham Hypoxia |
title_sort | normobaric intermittent hypoxia over 8 months does not reduce body weight and metabolic risk factors a randomized single blind placebo controlled study in normobaric hypoxia and normobaric sham hypoxia |
topic | Hypoxia Weight loss Physical exercise Obese Overweight |
url | http://www.karger.com/Article/FullText/431157 |
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