Castleman’s Disease Arising from the Hepatoduodenal Ligament Mimicking a Duodenal Gastrointestinal Stromal Tumor
Castleman’s disease (CD) arising from the hepatoduodenal ligament is extremely rare. A 32-year-old man was referred to a clinic with nausea. He was found to have an abdominal mass by ultrasonography and consulted our hospital for further examination. Computed tomography revealed an equally enhancing...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2021-04-01
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| Series: | Case Reports in Gastroenterology |
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| Online Access: | https://www.karger.com/Article/FullText/514394 |
| _version_ | 1818672182075588608 |
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| author | Koichi Oishi Kazuhiro Toyota Manabu Shimomura Tadateru Takahashi |
| author_facet | Koichi Oishi Kazuhiro Toyota Manabu Shimomura Tadateru Takahashi |
| author_sort | Koichi Oishi |
| collection | DOAJ |
| description | Castleman’s disease (CD) arising from the hepatoduodenal ligament is extremely rare. A 32-year-old man was referred to a clinic with nausea. He was found to have an abdominal mass by ultrasonography and consulted our hospital for further examination. Computed tomography revealed an equally enhancing mass, 5.2 cm in diameter, adjacent to the duodenum. On magnetic resonance imaging, the mass revealed a slightly iso-intensity signal equal to smooth muscle on T1-weighted imaging, a slightly high-intensity signal on T2-weighted imaging, and a high-intensity signal on diffusion-weighted imaging. Endoscopic ultrasonography showed a well-demarcated hypoechoic mass adjacent to the duodenum. The Doppler echo pattern indicated abundant blood flow. The preoperative diagnosis was a duodenal gastrointestinal stromal tumor. The patient underwent laparotomy and tumor excision. The finding of the intraoperative frozen section was CD. Histologically, the lymph follicles were markedly increased in number throughout the cortex and medulla with vascular proliferation and hyalinization in the intra- or extra-follicles. The germinal centers were atrophic and surrounded by concentrically arranged layers of small lymphocytes. The histological findings were the hyaline vascular variant of CD. If a hypervascular solid mass is detected in the abdomen, CD should be considered in the differential diagnosis. |
| first_indexed | 2024-12-17T07:35:49Z |
| format | Article |
| id | doaj.art-182043a3e7ee48f3a4514e1c2d3d2c21 |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-12-17T07:35:49Z |
| publishDate | 2021-04-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-182043a3e7ee48f3a4514e1c2d3d2c212022-12-21T21:58:19ZengKarger PublishersCase Reports in Gastroenterology1662-06312021-04-0115142443010.1159/000514394514394Castleman’s Disease Arising from the Hepatoduodenal Ligament Mimicking a Duodenal Gastrointestinal Stromal TumorKoichi Oishi0https://orcid.org/0000-0003-1159-3908Kazuhiro Toyota1Manabu Shimomura2Tadateru Takahashi3Department of Surgery, National Hospital Organization Higashihiroshima Medical Center, Higashihiroshima, JapanDepartment of Surgery, National Hospital Organization Higashihiroshima Medical Center, Higashihiroshima, JapanDepartment of Surgery, National Hospital Organization Higashihiroshima Medical Center, Higashihiroshima, JapanDepartment of Surgery, National Hospital Organization Higashihiroshima Medical Center, Higashihiroshima, JapanCastleman’s disease (CD) arising from the hepatoduodenal ligament is extremely rare. A 32-year-old man was referred to a clinic with nausea. He was found to have an abdominal mass by ultrasonography and consulted our hospital for further examination. Computed tomography revealed an equally enhancing mass, 5.2 cm in diameter, adjacent to the duodenum. On magnetic resonance imaging, the mass revealed a slightly iso-intensity signal equal to smooth muscle on T1-weighted imaging, a slightly high-intensity signal on T2-weighted imaging, and a high-intensity signal on diffusion-weighted imaging. Endoscopic ultrasonography showed a well-demarcated hypoechoic mass adjacent to the duodenum. The Doppler echo pattern indicated abundant blood flow. The preoperative diagnosis was a duodenal gastrointestinal stromal tumor. The patient underwent laparotomy and tumor excision. The finding of the intraoperative frozen section was CD. Histologically, the lymph follicles were markedly increased in number throughout the cortex and medulla with vascular proliferation and hyalinization in the intra- or extra-follicles. The germinal centers were atrophic and surrounded by concentrically arranged layers of small lymphocytes. The histological findings were the hyaline vascular variant of CD. If a hypervascular solid mass is detected in the abdomen, CD should be considered in the differential diagnosis.https://www.karger.com/Article/FullText/514394castleman’s diseaseduodenal gastrointestinal stromal tumorhepatoduodenal ligament |
| spellingShingle | Koichi Oishi Kazuhiro Toyota Manabu Shimomura Tadateru Takahashi Castleman’s Disease Arising from the Hepatoduodenal Ligament Mimicking a Duodenal Gastrointestinal Stromal Tumor Case Reports in Gastroenterology castleman’s disease duodenal gastrointestinal stromal tumor hepatoduodenal ligament |
| title | Castleman’s Disease Arising from the Hepatoduodenal Ligament Mimicking a Duodenal Gastrointestinal Stromal Tumor |
| title_full | Castleman’s Disease Arising from the Hepatoduodenal Ligament Mimicking a Duodenal Gastrointestinal Stromal Tumor |
| title_fullStr | Castleman’s Disease Arising from the Hepatoduodenal Ligament Mimicking a Duodenal Gastrointestinal Stromal Tumor |
| title_full_unstemmed | Castleman’s Disease Arising from the Hepatoduodenal Ligament Mimicking a Duodenal Gastrointestinal Stromal Tumor |
| title_short | Castleman’s Disease Arising from the Hepatoduodenal Ligament Mimicking a Duodenal Gastrointestinal Stromal Tumor |
| title_sort | castleman s disease arising from the hepatoduodenal ligament mimicking a duodenal gastrointestinal stromal tumor |
| topic | castleman’s disease duodenal gastrointestinal stromal tumor hepatoduodenal ligament |
| url | https://www.karger.com/Article/FullText/514394 |
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