Interrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory response
Introduction. There is noconsensus opinion regarding the connection of morphometric and biochemical changes in oral mucous membrane of animals with gastroduodenitis depending on the type of inflammatory response. For this reason, it remains important to study the relationship between changes in the...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2019-11-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/7564 |
| _version_ | 1811307237821382656 |
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| author | Ihor Mysula Valentyna Bondarchuk Gustaw Wójcik Walery Zukow Nataliya Sydliaruk Yuriy Mysula Marianna Mysula |
| author_facet | Ihor Mysula Valentyna Bondarchuk Gustaw Wójcik Walery Zukow Nataliya Sydliaruk Yuriy Mysula Marianna Mysula |
| author_sort | Ihor Mysula |
| collection | DOAJ |
| description | Introduction. There is noconsensus opinion regarding the connection of morphometric and biochemical changes in oral mucous membrane of animals with gastroduodenitis depending on the type of inflammatory response. For this reason, it remains important to study the relationship between changes in the morphometric parameters of the oral mucosa, lipid peroxidation indices and the antioxidant system under the influence of various types of inflammatory reaction in the conditions of experimental gastroduodenitis.
Material and methods. Experiments were carried out on 42 white male rats weighing 180-200 g housed under normal conditions on a standard vivarium diet; acute gastroduodenitis was simulated for 7 days by inserting by the probe into the stomach 0.25 ml of 10% solution C2H5OH and after 5 minutes 0.5 ml of 1.25% solution of HCl. Three different types of inflammatory response were also modeled.
Results. The most significant changes in oral mucosa on the basis of morphometric and biochemical parameters were found in animals with hyperergic type of inflammatory reaction. Rats with hypoergic type of inflammatory reaction had a lower depth of morphometric and biochemical changes. Morphometric changes were most significant on the tenth day of the experiment, regardless of the type of inflammatory reaction.
Conclusions. The obtained results confirm that changes in morphometric and biochemical parameters depend on the type of inflammatory reaction. |
| first_indexed | 2024-04-13T09:00:42Z |
| format | Article |
| id | doaj.art-18228d98930046d19440b9070ca4cd42 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-04-13T09:00:42Z |
| publishDate | 2019-11-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-18228d98930046d19440b9070ca4cd422022-12-22T02:53:09ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062019-11-01910223510.5281/zenodo.34717706646Interrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory responseIhor Mysula0Valentyna Bondarchuk1Gustaw Wójcik2Walery Zukow3Nataliya Sydliaruk4Yuriy Mysula5Marianna Mysula6I. Horbachevsky Ternopil National Medical University,TernopilI. Horbachevsky Ternopil National Medical University, TernopilPope John II State School of Higher Education in Biała PodlaskaNicolaus Copernicus University in Torun, TorunI. Horbachevsky Ternopil National Medical University, TernopilI. Horbachevsky Ternopil National Medical University, TernopilI. Horbachevsky Ternopil National Medical University, TernopilIntroduction. There is noconsensus opinion regarding the connection of morphometric and biochemical changes in oral mucous membrane of animals with gastroduodenitis depending on the type of inflammatory response. For this reason, it remains important to study the relationship between changes in the morphometric parameters of the oral mucosa, lipid peroxidation indices and the antioxidant system under the influence of various types of inflammatory reaction in the conditions of experimental gastroduodenitis. Material and methods. Experiments were carried out on 42 white male rats weighing 180-200 g housed under normal conditions on a standard vivarium diet; acute gastroduodenitis was simulated for 7 days by inserting by the probe into the stomach 0.25 ml of 10% solution C2H5OH and after 5 minutes 0.5 ml of 1.25% solution of HCl. Three different types of inflammatory response were also modeled. Results. The most significant changes in oral mucosa on the basis of morphometric and biochemical parameters were found in animals with hyperergic type of inflammatory reaction. Rats with hypoergic type of inflammatory reaction had a lower depth of morphometric and biochemical changes. Morphometric changes were most significant on the tenth day of the experiment, regardless of the type of inflammatory reaction. Conclusions. The obtained results confirm that changes in morphometric and biochemical parameters depend on the type of inflammatory reaction.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/7564cheekmucous membranemorphometric parametersbiochemical changestype of inflammatory responsegastroduodenitis. |
| spellingShingle | Ihor Mysula Valentyna Bondarchuk Gustaw Wójcik Walery Zukow Nataliya Sydliaruk Yuriy Mysula Marianna Mysula Interrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory response Journal of Education, Health and Sport cheek mucous membrane morphometric parameters biochemical changes type of inflammatory response gastroduodenitis. |
| title | Interrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory response |
| title_full | Interrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory response |
| title_fullStr | Interrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory response |
| title_full_unstemmed | Interrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory response |
| title_short | Interrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory response |
| title_sort | interrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory response |
| topic | cheek mucous membrane morphometric parameters biochemical changes type of inflammatory response gastroduodenitis. |
| url | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/7564 |
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